Acinetobacter infections prevalence and frequency of the antibiotics resistance: comparative study of intensive care units versus other hospital units
INTRODUCTION: this study aims to determine the Acinetobacter sp clinical isolates frequency and its antibiotic susceptibility pattern by comparing results obtained from the Intensive Care Units (ICUs) to that of other units at the Mohammed V Military Teaching Hospital in Rabat. METHODS: this is a re...
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| Format: | Article |
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The Pan African Medical Journal
2016-04-01
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| Series: | The Pan African Medical Journal |
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https://www.panafrican-med-journal.com/content/article/23/191/pdf/191.pdf
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| author | Jean Uwingabiye Mohammed Frikh Abdelhay Lemnouer Fatna Bssaibis Bouchra Belefquih Adil Maleb Souhail Dahraoui Lahcen Belyamani Abdelouahed Bait Charki Haimeur Lhoussain Louzi Azeddine Ibrahimi Mostafa Elouennass |
| author_facet | Jean Uwingabiye Mohammed Frikh Abdelhay Lemnouer Fatna Bssaibis Bouchra Belefquih Adil Maleb Souhail Dahraoui Lahcen Belyamani Abdelouahed Bait Charki Haimeur Lhoussain Louzi Azeddine Ibrahimi Mostafa Elouennass |
| author_sort | Jean Uwingabiye |
| collection | DOAJ |
| description | INTRODUCTION: this study aims to determine the Acinetobacter sp clinical isolates frequency and its antibiotic susceptibility pattern by comparing results obtained from the Intensive Care Units (ICUs) to that of other units at the Mohammed V Military Teaching Hospital in Rabat. METHODS: this is a retrospective study over a 2-years period where we collected all clinical isolates of Acinetobacter sp obtained from samples for infection diagnosis performed on hospitalized patients between 2012 to 2014. RESULTS: during the study period, 441 clinical and non-repetitive isolates of Acinetobacter sp were collected representing 6.94% of all bacterial clinical isolates (n=6352) and 9.6% of Gram negative rods (n=4569). More than a half of the isolates were from the ICUs and were obtained from 293 infected patients of which 65, 2% (191 cases) were males (sex ratio = 1.9) and the median age was 56 years (interquartile range: 42-68 years). Acinetobacter clinical isolates were obtained from respiratory samples (44.67%) followed by blood cultures (14.51%). The resistance to ciprofloxacin, ceftazidime, piperacillin / tazobactam, imipenem, amikacin, tobramycin, netilmicin,rifampicin and colistin was respectively 87%, 86%, 79%, 76%; 52%, 43%, 33% 32% and 1.7%. The difference in resistance between the ICUs and the other units was statistically significant (p =0.05) except for colistin, tetracycline and rifampicin. CONCLUSION: this paper shows that solving the problem of prevalence and high rate of multidrug resistant Acinetobacter infection which represents a therapeutic impasse, requires the control of the hospital environment and optimizing hands hygiene and antibiotics use in the hospital. |
| first_indexed | 2024-12-10T20:43:19Z |
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| institution | Directory Open Access Journal |
| issn | 1937-8688 1937-8688 |
| language | English |
| last_indexed | 2024-12-10T20:43:19Z |
| publishDate | 2016-04-01 |
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| spelling | doaj.art-b3a5de7bc44a44268689e7ff54b74ef02022-12-22T01:34:18ZengThe Pan African Medical JournalThe Pan African Medical Journal1937-86881937-86882016-04-012319110.11604/pamj.2016.23.191.79157915Acinetobacter infections prevalence and frequency of the antibiotics resistance: comparative study of intensive care units versus other hospital unitsJean Uwingabiye0Mohammed Frikh1Abdelhay Lemnouer2Fatna Bssaibis3Bouchra Belefquih4Adil Maleb5Souhail Dahraoui6Lahcen Belyamani7Abdelouahed Bait8Charki Haimeur9Lhoussain Louzi10Azeddine Ibrahimi11Mostafa Elouennass12 Service de Bactériologie, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc Service de Bactériologie, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc Service de Bactériologie, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc Service de Bactériologie, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc Service de Bactériologie, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc Service de Bactériologie, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc Service de Bactériologie, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc Service des Urgences, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc Services des Réanimations, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc Services des Réanimations, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc Equipe de recherche: épidémiologie et Résistance Bactérienne (ERB), Université Mohammed V, Faculté de Médecine et de Pharmacie, Rabat, Maroc Equipe de recherche: épidémiologie et Résistance Bactérienne (ERB), Université Mohammed V, Faculté de Médecine et de Pharmacie, Rabat, Maroc Service de Bactériologie, Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc INTRODUCTION: this study aims to determine the Acinetobacter sp clinical isolates frequency and its antibiotic susceptibility pattern by comparing results obtained from the Intensive Care Units (ICUs) to that of other units at the Mohammed V Military Teaching Hospital in Rabat. METHODS: this is a retrospective study over a 2-years period where we collected all clinical isolates of Acinetobacter sp obtained from samples for infection diagnosis performed on hospitalized patients between 2012 to 2014. RESULTS: during the study period, 441 clinical and non-repetitive isolates of Acinetobacter sp were collected representing 6.94% of all bacterial clinical isolates (n=6352) and 9.6% of Gram negative rods (n=4569). More than a half of the isolates were from the ICUs and were obtained from 293 infected patients of which 65, 2% (191 cases) were males (sex ratio = 1.9) and the median age was 56 years (interquartile range: 42-68 years). Acinetobacter clinical isolates were obtained from respiratory samples (44.67%) followed by blood cultures (14.51%). The resistance to ciprofloxacin, ceftazidime, piperacillin / tazobactam, imipenem, amikacin, tobramycin, netilmicin,rifampicin and colistin was respectively 87%, 86%, 79%, 76%; 52%, 43%, 33% 32% and 1.7%. The difference in resistance between the ICUs and the other units was statistically significant (p =0.05) except for colistin, tetracycline and rifampicin. CONCLUSION: this paper shows that solving the problem of prevalence and high rate of multidrug resistant Acinetobacter infection which represents a therapeutic impasse, requires the control of the hospital environment and optimizing hands hygiene and antibiotics use in the hospital. https://www.panafrican-med-journal.com/content/article/23/191/pdf/191.pdf acinetobacterprevalenceantibiotic resistance intensive care units |
| spellingShingle | Jean Uwingabiye Mohammed Frikh Abdelhay Lemnouer Fatna Bssaibis Bouchra Belefquih Adil Maleb Souhail Dahraoui Lahcen Belyamani Abdelouahed Bait Charki Haimeur Lhoussain Louzi Azeddine Ibrahimi Mostafa Elouennass Acinetobacter infections prevalence and frequency of the antibiotics resistance: comparative study of intensive care units versus other hospital units The Pan African Medical Journal acinetobacter prevalence antibiotic resistance intensive care units |
| title | Acinetobacter infections prevalence and frequency of the antibiotics resistance: comparative study of intensive care units versus other hospital units |
| title_full | Acinetobacter infections prevalence and frequency of the antibiotics resistance: comparative study of intensive care units versus other hospital units |
| title_fullStr | Acinetobacter infections prevalence and frequency of the antibiotics resistance: comparative study of intensive care units versus other hospital units |
| title_full_unstemmed | Acinetobacter infections prevalence and frequency of the antibiotics resistance: comparative study of intensive care units versus other hospital units |
| title_short | Acinetobacter infections prevalence and frequency of the antibiotics resistance: comparative study of intensive care units versus other hospital units |
| title_sort | acinetobacter infections prevalence and frequency of the antibiotics resistance comparative study of intensive care units versus other hospital units |
| topic | acinetobacter prevalence antibiotic resistance intensive care units |
| url |
https://www.panafrican-med-journal.com/content/article/23/191/pdf/191.pdf
|
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