Organisms isolated from adults with Cystic Fibrosis
<p>Abstract</p> <p>Background</p> <p>Patients with cystic fibrosis [CF] have frequent pulmonary exacerbations associated with the isolation of bacterial organisms from sputum samples. It is not clear however, if there are differences in the types of additional organisms...
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| Format: | Article |
| Language: | English |
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BMC
2004-12-01
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| Series: | Annals of Clinical Microbiology and Antimicrobials |
| Subjects: | |
| Online Access: | http://www.ann-clinmicrob.com/content/3/1/26 |
| _version_ | 1811266244184113152 |
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| author | Moore John E McDowell Andrew McManus Terence E Elborn Stuart J |
| author_facet | Moore John E McDowell Andrew McManus Terence E Elborn Stuart J |
| author_sort | Moore John E |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Patients with cystic fibrosis [CF] have frequent pulmonary exacerbations associated with the isolation of bacterial organisms from sputum samples. It is not clear however, if there are differences in the types of additional organisms isolated from patients who are infected with <it>Burkholderia cepacia </it>complex [BCC] or <it>Pseudomonas aerugionsa </it>[PA] in comparison to those who are not infected with either of these organisms [NI].</p> <p>Methods</p> <p>Adult patients attending the regional CF unit were followed over a two year period and patients were assigned to three groups depending on whether they were known to be chronically infected with BCC, PA or NI. We compared the numbers and types of organisms which were isolated in each of these groups.</p> <p>Results</p> <p>Information was available on a total of 79 patients; BCC 23, PA 30 and NI 26. Total numbers of organisms isolated, expressed as median and IQR for each group, [P = 0.045] and numbers of co-infecting organisms [P = 0.003] were significantly higher in the BCC group compared to PA, and in the PA group [P < 0.001, p = 0.007 respectively] compared to NI patients. The pattern of co-infecting organisms was similar in all three groups.</p> <p>Conclusions</p> <p>Total numbers of organisms isolated and numbers of co-infecting organisms were significantly higher in the BCC group compared to PA, and in the PA group compared to NI patients. Types of co-infecting organisms are similar in all groups of patients.</p> |
| first_indexed | 2024-04-12T20:38:35Z |
| format | Article |
| id | doaj.art-b3a8013fd01e47faa3de4b5cb6805b90 |
| institution | Directory Open Access Journal |
| issn | 1476-0711 |
| language | English |
| last_indexed | 2024-04-12T20:38:35Z |
| publishDate | 2004-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Annals of Clinical Microbiology and Antimicrobials |
| spelling | doaj.art-b3a8013fd01e47faa3de4b5cb6805b902022-12-22T03:17:30ZengBMCAnnals of Clinical Microbiology and Antimicrobials1476-07112004-12-01312610.1186/1476-0711-3-26Organisms isolated from adults with Cystic FibrosisMoore John EMcDowell AndrewMcManus Terence EElborn Stuart J<p>Abstract</p> <p>Background</p> <p>Patients with cystic fibrosis [CF] have frequent pulmonary exacerbations associated with the isolation of bacterial organisms from sputum samples. It is not clear however, if there are differences in the types of additional organisms isolated from patients who are infected with <it>Burkholderia cepacia </it>complex [BCC] or <it>Pseudomonas aerugionsa </it>[PA] in comparison to those who are not infected with either of these organisms [NI].</p> <p>Methods</p> <p>Adult patients attending the regional CF unit were followed over a two year period and patients were assigned to three groups depending on whether they were known to be chronically infected with BCC, PA or NI. We compared the numbers and types of organisms which were isolated in each of these groups.</p> <p>Results</p> <p>Information was available on a total of 79 patients; BCC 23, PA 30 and NI 26. Total numbers of organisms isolated, expressed as median and IQR for each group, [P = 0.045] and numbers of co-infecting organisms [P = 0.003] were significantly higher in the BCC group compared to PA, and in the PA group [P < 0.001, p = 0.007 respectively] compared to NI patients. The pattern of co-infecting organisms was similar in all three groups.</p> <p>Conclusions</p> <p>Total numbers of organisms isolated and numbers of co-infecting organisms were significantly higher in the BCC group compared to PA, and in the PA group compared to NI patients. Types of co-infecting organisms are similar in all groups of patients.</p>http://www.ann-clinmicrob.com/content/3/1/26Cystic FibrosisBacterial InfectionAntibiotics<it>Burkholderia cepacia complex</it><it>Pseudomonas aeruginosa</it> |
| spellingShingle | Moore John E McDowell Andrew McManus Terence E Elborn Stuart J Organisms isolated from adults with Cystic Fibrosis Annals of Clinical Microbiology and Antimicrobials Cystic Fibrosis Bacterial Infection Antibiotics <it>Burkholderia cepacia complex</it> <it>Pseudomonas aeruginosa</it> |
| title | Organisms isolated from adults with Cystic Fibrosis |
| title_full | Organisms isolated from adults with Cystic Fibrosis |
| title_fullStr | Organisms isolated from adults with Cystic Fibrosis |
| title_full_unstemmed | Organisms isolated from adults with Cystic Fibrosis |
| title_short | Organisms isolated from adults with Cystic Fibrosis |
| title_sort | organisms isolated from adults with cystic fibrosis |
| topic | Cystic Fibrosis Bacterial Infection Antibiotics <it>Burkholderia cepacia complex</it> <it>Pseudomonas aeruginosa</it> |
| url | http://www.ann-clinmicrob.com/content/3/1/26 |
| work_keys_str_mv | AT moorejohne organismsisolatedfromadultswithcysticfibrosis AT mcdowellandrew organismsisolatedfromadultswithcysticfibrosis AT mcmanusterencee organismsisolatedfromadultswithcysticfibrosis AT elbornstuartj organismsisolatedfromadultswithcysticfibrosis |