Spindle and Giant Cell Type Undifferentiated Carcinoma of the Proximal Bile Duct
Undifferentiated spindle and giant cell carcinoma is an extremely rare malignant neoplasm arising in the extrahepatic bile duct. We herein present the case of a 67-year-old male who developed an undifferentiated spindle and giant cell carcinoma of the proximal bile duct. A nodular infiltrating tumor...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2012-01-01
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| Series: | Case Reports in Gastroenterology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/336198 |
| _version_ | 1798045598478237696 |
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| author | Takao Ide Atsushi Miyoshi Kenji Kitahara Keita Kai Hirokazu Noshiro |
| author_facet | Takao Ide Atsushi Miyoshi Kenji Kitahara Keita Kai Hirokazu Noshiro |
| author_sort | Takao Ide |
| collection | DOAJ |
| description | Undifferentiated spindle and giant cell carcinoma is an extremely rare malignant neoplasm arising in the extrahepatic bile duct. We herein present the case of a 67-year-old male who developed an undifferentiated spindle and giant cell carcinoma of the proximal bile duct. A nodular infiltrating tumor was located at the proximal bile duct, resulting in obstructive jaundice. Histologically, the tumor was composed of mainly spindle-shaped and giant cells and showed positive immunoreactivity for both cytokeratin and vimentin. Adjuvant chemotherapy was administered following extrahepatic bile duct resection, and he has been doing well for 16 months since the surgical treatment. The literature on this rare malignancy is also reviewed and discussed. |
| first_indexed | 2024-04-11T23:24:42Z |
| format | Article |
| id | doaj.art-b3a927a3a17141549bc690e617b7b8e1 |
| institution | Directory Open Access Journal |
| issn | 1662-0631 |
| language | English |
| last_indexed | 2024-04-11T23:24:42Z |
| publishDate | 2012-01-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj.art-b3a927a3a17141549bc690e617b7b8e12022-12-22T03:57:22ZengKarger PublishersCase Reports in Gastroenterology1662-06312012-01-0161333910.1159/000336198336198Spindle and Giant Cell Type Undifferentiated Carcinoma of the Proximal Bile DuctTakao IdeAtsushi MiyoshiKenji KitaharaKeita KaiHirokazu NoshiroUndifferentiated spindle and giant cell carcinoma is an extremely rare malignant neoplasm arising in the extrahepatic bile duct. We herein present the case of a 67-year-old male who developed an undifferentiated spindle and giant cell carcinoma of the proximal bile duct. A nodular infiltrating tumor was located at the proximal bile duct, resulting in obstructive jaundice. Histologically, the tumor was composed of mainly spindle-shaped and giant cells and showed positive immunoreactivity for both cytokeratin and vimentin. Adjuvant chemotherapy was administered following extrahepatic bile duct resection, and he has been doing well for 16 months since the surgical treatment. The literature on this rare malignancy is also reviewed and discussed.http://www.karger.com/Article/FullText/336198Bile duct cancerBile duct resectionAdjuvant chemotherapy |
| spellingShingle | Takao Ide Atsushi Miyoshi Kenji Kitahara Keita Kai Hirokazu Noshiro Spindle and Giant Cell Type Undifferentiated Carcinoma of the Proximal Bile Duct Case Reports in Gastroenterology Bile duct cancer Bile duct resection Adjuvant chemotherapy |
| title | Spindle and Giant Cell Type Undifferentiated Carcinoma of the Proximal Bile Duct |
| title_full | Spindle and Giant Cell Type Undifferentiated Carcinoma of the Proximal Bile Duct |
| title_fullStr | Spindle and Giant Cell Type Undifferentiated Carcinoma of the Proximal Bile Duct |
| title_full_unstemmed | Spindle and Giant Cell Type Undifferentiated Carcinoma of the Proximal Bile Duct |
| title_short | Spindle and Giant Cell Type Undifferentiated Carcinoma of the Proximal Bile Duct |
| title_sort | spindle and giant cell type undifferentiated carcinoma of the proximal bile duct |
| topic | Bile duct cancer Bile duct resection Adjuvant chemotherapy |
| url | http://www.karger.com/Article/FullText/336198 |
| work_keys_str_mv | AT takaoide spindleandgiantcelltypeundifferentiatedcarcinomaoftheproximalbileduct AT atsushimiyoshi spindleandgiantcelltypeundifferentiatedcarcinomaoftheproximalbileduct AT kenjikitahara spindleandgiantcelltypeundifferentiatedcarcinomaoftheproximalbileduct AT keitakai spindleandgiantcelltypeundifferentiatedcarcinomaoftheproximalbileduct AT hirokazunoshiro spindleandgiantcelltypeundifferentiatedcarcinomaoftheproximalbileduct |