Probiotics Exhibit Strain-Specific Protective Effects in T84 Cells Challenged With Clostridioides difficile-Infected Fecal Water

Probiotics Exhibit Strain-Specific Protective Effects in T84 Cells Challenged With Clostridioides difficile-Infected Fecal Water

Clostridioides difficile infection (CDI) is frequently associated with intestinal injury and mucosal barrier dysfunction, leading to an inflammatory response involving neutrophil localization and upregulation of pro-inflammatory cytokines. The severity of clinical manifestations is associated with t...

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Bibliographic Details
Main Authors: Mohd Baasir Gaisawat, Silvia Lopez-Escalera, Chad W. MacPherson, Michèle M. Iskandar, Thomas A. Tompkins, Stan Kubow
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Microbiology
Subjects:
probiotics
T84 cells
C. difficile
inflammation
cytokines
cytotoxicity
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.698638/full

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