PEGylated crushed gold shell-radiolabeled core nanoballs for in vivo tumor imaging with dual positron emission tomography and Cerenkov luminescent imaging

PEGylated crushed gold shell-radiolabeled core nanoballs for in vivo tumor imaging with dual positron emission tomography and Cerenkov luminescent imaging

Abstract Background Radioactive isotope-labeled gold nanomaterials have potential biomedical applications. Here, we report the synthesis and characterization of PEGylated crushed gold shell-radioactive iodide-124-labeled gold core nanoballs (PEG-124I-Au@AuCBs) for in vivo tumor imaging applications...

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Bibliographic Details
Main Authors: Sang Bong Lee, Dinesh Kumar, Yinghua Li, In-Kyu Lee, Sung Jin Cho, Sang Kyoon Kim, Sang-Woo Lee, Shin Young Jeong, Jaetae Lee, Yong Hyun Jeon
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Journal of Nanobiotechnology
Subjects:
Gold nanoparticles
Crushed gold shells
Radioactive iodine-124
Nuclear medicine imaging
Cerenkov luminescent imaging
Tumor imaging
Online Access:http://link.springer.com/article/10.1186/s12951-018-0366-x

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