Endometrial changes after methotrexate treatment: Relation with multiple nabothian cysts and future pregnancies
A clinical study was conducted in order to validate the effect of methotrexate on 30 patients with ectopic pregnancy (EP). A typical ultrasound appearance of multiple cysts of Naboth in the cervix was observed on six cases that are studied below. Endometrial sample with endogyn was retrieved from th...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2016-08-01
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| Series: | European Journal of Inflammation |
| Online Access: | https://doi.org/10.1177/1721727X16656861 |
| _version_ | 1819210398588469248 |
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| author | Dimitrios Balaouras Dimitrios Chitzios Angelos Daniilidis Theocharis Tantanasis Georgios Mavromatidis Aristotelis Loufopoulos Maria Nasioutziki Efstratios Asimakopoulos |
| author_facet | Dimitrios Balaouras Dimitrios Chitzios Angelos Daniilidis Theocharis Tantanasis Georgios Mavromatidis Aristotelis Loufopoulos Maria Nasioutziki Efstratios Asimakopoulos |
| author_sort | Dimitrios Balaouras |
| collection | DOAJ |
| description | A clinical study was conducted in order to validate the effect of methotrexate on 30 patients with ectopic pregnancy (EP). A typical ultrasound appearance of multiple cysts of Naboth in the cervix was observed on six cases that are studied below. Endometrial sample with endogyn was retrieved from the six cases after the treatment with methotrexate was complete. The cytological results were studied and there were many changes found in the endometrial cells, in their cores, and some inflammatory cells as well. Two out of the six cases studied show more profound evidence. The cellular appearance of the endometrium after the treatment is discussed, in relation to the presence of multiple Nabothian cysts, as a result of inflammatory reaction, and the possibility of any influence in the capacity for a future pregnancy. |
| first_indexed | 2024-12-23T06:10:33Z |
| format | Article |
| id | doaj.art-b3b1a170110541ee8fde84c9e32b0018 |
| institution | Directory Open Access Journal |
| issn | 1721-727X |
| language | English |
| last_indexed | 2024-12-23T06:10:33Z |
| publishDate | 2016-08-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | European Journal of Inflammation |
| spelling | doaj.art-b3b1a170110541ee8fde84c9e32b00182022-12-21T17:57:27ZengSAGE PublishingEuropean Journal of Inflammation1721-727X2016-08-011410.1177/1721727X16656861Endometrial changes after methotrexate treatment: Relation with multiple nabothian cysts and future pregnanciesDimitrios Balaouras0Dimitrios Chitzios1Angelos Daniilidis2Theocharis Tantanasis3Georgios Mavromatidis4Aristotelis Loufopoulos5Maria Nasioutziki6Efstratios Asimakopoulos72nd University Department of Obstetrics and Gynecology, Hippokrateio General Hospital, Aristotle University of Thessaloniki, Greece2nd University Department of Obstetrics and Gynecology, Hippokrateio General Hospital, Aristotle University of Thessaloniki, Greece2nd University Department of Obstetrics and Gynecology, Hippokrateio General Hospital, Aristotle University of Thessaloniki, Greece2nd University Department of Obstetrics and Gynecology, Hippokrateio General Hospital, Aristotle University of Thessaloniki, Greece3rd University Department of Obstetrics and Gynecology, Hippokrateio General Hospital, Aristotle University of Thessaloniki, Greece2nd University Department of Obstetrics and Gynecology, Hippokrateio General Hospital, Aristotle University of Thessaloniki, GreeceDepartment of Cytology, Hippokrateio General Hospital, Aristotle University of Thessaloniki, Greece2nd University Department of Obstetrics and Gynecology, Hippokrateio General Hospital, Aristotle University of Thessaloniki, GreeceA clinical study was conducted in order to validate the effect of methotrexate on 30 patients with ectopic pregnancy (EP). A typical ultrasound appearance of multiple cysts of Naboth in the cervix was observed on six cases that are studied below. Endometrial sample with endogyn was retrieved from the six cases after the treatment with methotrexate was complete. The cytological results were studied and there were many changes found in the endometrial cells, in their cores, and some inflammatory cells as well. Two out of the six cases studied show more profound evidence. The cellular appearance of the endometrium after the treatment is discussed, in relation to the presence of multiple Nabothian cysts, as a result of inflammatory reaction, and the possibility of any influence in the capacity for a future pregnancy.https://doi.org/10.1177/1721727X16656861 |
| spellingShingle | Dimitrios Balaouras Dimitrios Chitzios Angelos Daniilidis Theocharis Tantanasis Georgios Mavromatidis Aristotelis Loufopoulos Maria Nasioutziki Efstratios Asimakopoulos Endometrial changes after methotrexate treatment: Relation with multiple nabothian cysts and future pregnancies European Journal of Inflammation |
| title | Endometrial changes after methotrexate treatment: Relation with multiple nabothian cysts and future pregnancies |
| title_full | Endometrial changes after methotrexate treatment: Relation with multiple nabothian cysts and future pregnancies |
| title_fullStr | Endometrial changes after methotrexate treatment: Relation with multiple nabothian cysts and future pregnancies |
| title_full_unstemmed | Endometrial changes after methotrexate treatment: Relation with multiple nabothian cysts and future pregnancies |
| title_short | Endometrial changes after methotrexate treatment: Relation with multiple nabothian cysts and future pregnancies |
| title_sort | endometrial changes after methotrexate treatment relation with multiple nabothian cysts and future pregnancies |
| url | https://doi.org/10.1177/1721727X16656861 |
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