Nile Tilapia Skin Impregnated with Antibacterial Silver/Titanium Dioxide Compounds
The development of alternative (and free-of-antibiotics) antibacterial and antibiofilm agents is an important strategy to circumvent the resistance of bacteria to antibiotics. Herein, we explore the production of mixed oxides by incorporating silver nanoparticles in titanium dioxide as a silver conc...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Applied Microbiology |
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| Online Access: | https://www.mdpi.com/2673-8007/3/1/18 |
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| author | Maíra Cristina Marcolino Milena Lima Guimarães Jorge Alexandre Alencar Fotius Leda Maria Saragiotto Colpini Mateus Matiuzzi da Costa Helinando Pequeno de Oliveira |
| author_facet | Maíra Cristina Marcolino Milena Lima Guimarães Jorge Alexandre Alencar Fotius Leda Maria Saragiotto Colpini Mateus Matiuzzi da Costa Helinando Pequeno de Oliveira |
| author_sort | Maíra Cristina Marcolino |
| collection | DOAJ |
| description | The development of alternative (and free-of-antibiotics) antibacterial and antibiofilm agents is an important strategy to circumvent the resistance of bacteria to antibiotics. Herein, we explore the production of mixed oxides by incorporating silver nanoparticles in titanium dioxide as a silver concentration-dependent antibacterial agent that is further incorporated in Tilapia fish skin (a promising prototype of xenograft), integrating the antibacterial activity of mixed oxide into the intrinsic properties of Tilapia skin. The antibiofilm activity of samples prepared with high concentrations of silver (10 wt% of precursor AgNO<sub>3</sub>) has been considered a good antibiofilm response. The influence of silver content is also observed with respect to the minimum bactericidal concentration, which is reduced to 3.13 mg/mL with a characteristic kill time in the order of 30 min that is associated with antibiofilm activity in biofilm-forming strains of <i>Staphylococcus aureus</i>. These results indicate that modified Tilapia fish skin acquires antibacterial behavior and can be explored for xenografts with prospective applications in the light-dependent actuation of TiO<sub>2</sub>-based compounds. |
| first_indexed | 2024-03-11T06:59:51Z |
| format | Article |
| id | doaj.art-b3b22cc12d1c417883e8edf10e4cbc2b |
| institution | Directory Open Access Journal |
| issn | 2673-8007 |
| language | English |
| last_indexed | 2024-03-11T06:59:51Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Microbiology |
| spelling | doaj.art-b3b22cc12d1c417883e8edf10e4cbc2b2023-11-17T09:20:41ZengMDPI AGApplied Microbiology2673-80072023-02-013126527510.3390/applmicrobiol3010018Nile Tilapia Skin Impregnated with Antibacterial Silver/Titanium Dioxide CompoundsMaíra Cristina Marcolino0Milena Lima Guimarães1Jorge Alexandre Alencar Fotius2Leda Maria Saragiotto Colpini3Mateus Matiuzzi da Costa4Helinando Pequeno de Oliveira5Institute of Materials Science, Federal University of São Francisco Valley, Avenida Antônio Carlos Magalhães, 510-Santo Antônio, Juazeiro 48902-300, CEP, BrazilInstitute of Materials Science, Federal University of São Francisco Valley, Avenida Antônio Carlos Magalhães, 510-Santo Antônio, Juazeiro 48902-300, CEP, BrazilInstitute of Materials Science, Federal University of São Francisco Valley, Avenida Antônio Carlos Magalhães, 510-Santo Antônio, Juazeiro 48902-300, CEP, BrazilCurso Superior de Tecnologia em Biocombustíveis, Setor Palotina, Federal University of Parana, Rua Pioneiro 2153, Jardim Dallas, Palotina 85950-000, CEP, BrazilInstitute of Materials Science, Federal University of São Francisco Valley, Avenida Antônio Carlos Magalhães, 510-Santo Antônio, Juazeiro 48902-300, CEP, BrazilInstitute of Materials Science, Federal University of São Francisco Valley, Avenida Antônio Carlos Magalhães, 510-Santo Antônio, Juazeiro 48902-300, CEP, BrazilThe development of alternative (and free-of-antibiotics) antibacterial and antibiofilm agents is an important strategy to circumvent the resistance of bacteria to antibiotics. Herein, we explore the production of mixed oxides by incorporating silver nanoparticles in titanium dioxide as a silver concentration-dependent antibacterial agent that is further incorporated in Tilapia fish skin (a promising prototype of xenograft), integrating the antibacterial activity of mixed oxide into the intrinsic properties of Tilapia skin. The antibiofilm activity of samples prepared with high concentrations of silver (10 wt% of precursor AgNO<sub>3</sub>) has been considered a good antibiofilm response. The influence of silver content is also observed with respect to the minimum bactericidal concentration, which is reduced to 3.13 mg/mL with a characteristic kill time in the order of 30 min that is associated with antibiofilm activity in biofilm-forming strains of <i>Staphylococcus aureus</i>. These results indicate that modified Tilapia fish skin acquires antibacterial behavior and can be explored for xenografts with prospective applications in the light-dependent actuation of TiO<sub>2</sub>-based compounds.https://www.mdpi.com/2673-8007/3/1/18nanomaterialssilver nanoparticlesmixed oxidexenograftantibiofilm<i>S. aureus</i> |
| spellingShingle | Maíra Cristina Marcolino Milena Lima Guimarães Jorge Alexandre Alencar Fotius Leda Maria Saragiotto Colpini Mateus Matiuzzi da Costa Helinando Pequeno de Oliveira Nile Tilapia Skin Impregnated with Antibacterial Silver/Titanium Dioxide Compounds Applied Microbiology nanomaterials silver nanoparticles mixed oxide xenograft antibiofilm <i>S. aureus</i> |
| title | Nile Tilapia Skin Impregnated with Antibacterial Silver/Titanium Dioxide Compounds |
| title_full | Nile Tilapia Skin Impregnated with Antibacterial Silver/Titanium Dioxide Compounds |
| title_fullStr | Nile Tilapia Skin Impregnated with Antibacterial Silver/Titanium Dioxide Compounds |
| title_full_unstemmed | Nile Tilapia Skin Impregnated with Antibacterial Silver/Titanium Dioxide Compounds |
| title_short | Nile Tilapia Skin Impregnated with Antibacterial Silver/Titanium Dioxide Compounds |
| title_sort | nile tilapia skin impregnated with antibacterial silver titanium dioxide compounds |
| topic | nanomaterials silver nanoparticles mixed oxide xenograft antibiofilm <i>S. aureus</i> |
| url | https://www.mdpi.com/2673-8007/3/1/18 |
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