HBsAg in Cord Blood Qf Newborns of HBsAg-Positive Mothers

Vertical transmission of hepatitis B infection that may occur during pregnancy at delivery-, in infancy, and early childhood has an important role in the development of chronic hepatitis B. Intrauterine infection is suspected to occur when hepatitis B viruses cross the placenta into fetal circulatio...

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Main Authors: Adnan S. Wiharta, Evi Setiadi, H. M. Sjaifullah Noer, Triyatmo Rachimhadhi, Asri Rasad
Format: Article
Language:English
Published: Indonesian Pediatric Society Publishing House 2018-11-01
Series:Paediatrica Indonesiana
Subjects:
Online Access:https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2020
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author Adnan S. Wiharta
Evi Setiadi
H. M. Sjaifullah Noer
Triyatmo Rachimhadhi
Asri Rasad
author_facet Adnan S. Wiharta
Evi Setiadi
H. M. Sjaifullah Noer
Triyatmo Rachimhadhi
Asri Rasad
author_sort Adnan S. Wiharta
collection DOAJ
description Vertical transmission of hepatitis B infection that may occur during pregnancy at delivery-, in infancy, and early childhood has an important role in the development of chronic hepatitis B. Intrauterine infection is suspected to occur when hepatitis B viruses cross the placenta into fetal circulation due to failure of placental tissue function. In Cipto Mangunkusumo Hospital, Jakarta, 98 (6.4%) of 1536 pregnant mothers obseiVed during 3 years (1987 -1990) showed positive HBsAg. Six (8.3%) of 60 babies of born to HBsAg positive mothers showed positive HBsAg in their cord blood, but this disappeared after one month. All babies born to HBsAg positive mothers were vaccinated on months 0, 1, 2, and 12. HBsAg in cord blood might not play an important role in vertical transmission.
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spelling doaj.art-b3b5a9ba4409450abd46d15075d7af302022-12-22T01:11:44ZengIndonesian Pediatric Society Publishing HousePaediatrica Indonesiana0030-93112338-476X2018-11-01345-6125810.14238/pi34.5-6.1994.125-82020HBsAg in Cord Blood Qf Newborns of HBsAg-Positive MothersAdnan S. Wiharta0Evi Setiadi1H. M. Sjaifullah Noer2Triyatmo Rachimhadhi3Asri Rasad4Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, JakartaDepartment of Biochemistry, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, JakartaUniversitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, JakartaDepartment of Obstetrics & Gynaecology, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, JakartaDepartment of Biochemistry, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, JakartaVertical transmission of hepatitis B infection that may occur during pregnancy at delivery-, in infancy, and early childhood has an important role in the development of chronic hepatitis B. Intrauterine infection is suspected to occur when hepatitis B viruses cross the placenta into fetal circulation due to failure of placental tissue function. In Cipto Mangunkusumo Hospital, Jakarta, 98 (6.4%) of 1536 pregnant mothers obseiVed during 3 years (1987 -1990) showed positive HBsAg. Six (8.3%) of 60 babies of born to HBsAg positive mothers showed positive HBsAg in their cord blood, but this disappeared after one month. All babies born to HBsAg positive mothers were vaccinated on months 0, 1, 2, and 12. HBsAg in cord blood might not play an important role in vertical transmission.https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2020HBsAg; cord bloos; HBsAg positive; vertical transmission; hepatitis B
spellingShingle Adnan S. Wiharta
Evi Setiadi
H. M. Sjaifullah Noer
Triyatmo Rachimhadhi
Asri Rasad
HBsAg in Cord Blood Qf Newborns of HBsAg-Positive Mothers
Paediatrica Indonesiana
HBsAg; cord bloos; HBsAg positive; vertical transmission; hepatitis B
title HBsAg in Cord Blood Qf Newborns of HBsAg-Positive Mothers
title_full HBsAg in Cord Blood Qf Newborns of HBsAg-Positive Mothers
title_fullStr HBsAg in Cord Blood Qf Newborns of HBsAg-Positive Mothers
title_full_unstemmed HBsAg in Cord Blood Qf Newborns of HBsAg-Positive Mothers
title_short HBsAg in Cord Blood Qf Newborns of HBsAg-Positive Mothers
title_sort hbsag in cord blood qf newborns of hbsag positive mothers
topic HBsAg; cord bloos; HBsAg positive; vertical transmission; hepatitis B
url https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2020
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