Trifocal choroidal melanoma in an eye with oculodermal melanocytosis: A case report

We report a case of trifocal choroidal melanoma (three separate tumors) in a 48-year-old Caucasian female who had been followed for oculodermal melanocytosis since childhood. At presentation, no tumor was present and annual examination was advised. Seventeen years later, three choroidal melanocytic...

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Main Authors: Samuel J Fallon, Charlotte N Shields, Maura Di Nicola
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=12;spage=2092;epage=2094;aulast=Fallon
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author Samuel J Fallon
Charlotte N Shields
Maura Di Nicola
author_facet Samuel J Fallon
Charlotte N Shields
Maura Di Nicola
author_sort Samuel J Fallon
collection DOAJ
description We report a case of trifocal choroidal melanoma (three separate tumors) in a 48-year-old Caucasian female who had been followed for oculodermal melanocytosis since childhood. At presentation, no tumor was present and annual examination was advised. Seventeen years later, three choroidal melanocytic lesions were detected in the right eye. Growth of each was documented, enucleation was performed, and histopathology revealed three independent choroidal melanomas. The patient developed extensive liver and bone metastases and subsequently died. Oculodermal melanocytosis is a risk factor for the development of uveal melanoma and a potential marker for worse prognosis. Careful long-term follow-up is required.
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spelling doaj.art-b3b775ada5674b4b9a2567082ad841232022-12-21T18:19:20ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892019-01-0167122092209410.4103/ijo.IJO_493_19Trifocal choroidal melanoma in an eye with oculodermal melanocytosis: A case reportSamuel J FallonCharlotte N ShieldsMaura Di NicolaWe report a case of trifocal choroidal melanoma (three separate tumors) in a 48-year-old Caucasian female who had been followed for oculodermal melanocytosis since childhood. At presentation, no tumor was present and annual examination was advised. Seventeen years later, three choroidal melanocytic lesions were detected in the right eye. Growth of each was documented, enucleation was performed, and histopathology revealed three independent choroidal melanomas. The patient developed extensive liver and bone metastases and subsequently died. Oculodermal melanocytosis is a risk factor for the development of uveal melanoma and a potential marker for worse prognosis. Careful long-term follow-up is required.http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=12;spage=2092;epage=2094;aulast=Fallonchoroidmelanocytosismelanomamultifocaltrifocal
spellingShingle Samuel J Fallon
Charlotte N Shields
Maura Di Nicola
Trifocal choroidal melanoma in an eye with oculodermal melanocytosis: A case report
Indian Journal of Ophthalmology
choroid
melanocytosis
melanoma
multifocal
trifocal
title Trifocal choroidal melanoma in an eye with oculodermal melanocytosis: A case report
title_full Trifocal choroidal melanoma in an eye with oculodermal melanocytosis: A case report
title_fullStr Trifocal choroidal melanoma in an eye with oculodermal melanocytosis: A case report
title_full_unstemmed Trifocal choroidal melanoma in an eye with oculodermal melanocytosis: A case report
title_short Trifocal choroidal melanoma in an eye with oculodermal melanocytosis: A case report
title_sort trifocal choroidal melanoma in an eye with oculodermal melanocytosis a case report
topic choroid
melanocytosis
melanoma
multifocal
trifocal
url http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=12;spage=2092;epage=2094;aulast=Fallon
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AT charlottenshields trifocalchoroidalmelanomainaneyewithoculodermalmelanocytosisacasereport
AT mauradinicola trifocalchoroidalmelanomainaneyewithoculodermalmelanocytosisacasereport