Sinonasal Synovial Sarcoma Masquerading as A Common Soft Tissue Tumor: A Diagnostic Challenge and Literature Review

Synovial sarcoma is a malignant soft tissue neoplasm which amounts to 7-10% of all sarcomas. Clinicopathological heterogeneity within this tumour creates a diagnostic challenge in sorting it out from its differential diagnoses. Here we report a 42-year-old female patient presenting with a m...

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Main Authors: Pranshu Saklani, Shruthi N Shetageri, S R Raja Parthiban
Format: Article
Language:English
Published: ADICHUNCHANAGIRI INSTITUTE OF MEDICAL SCIENCES 2022-12-01
Series:Journal of Medical Sciences and Health
Online Access:https://jmsh.ac.in/articles/sinonasal-synovial-sarcoma-masquerading-as-a-common-soft-tissue-tumor-a-diagnostic-challenge-and-literature-review
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author Pranshu Saklani
Shruthi N Shetageri
S R Raja Parthiban
author_facet Pranshu Saklani
Shruthi N Shetageri
S R Raja Parthiban
author_sort Pranshu Saklani
collection DOAJ
description Synovial sarcoma is a malignant soft tissue neoplasm which amounts to 7-10% of all sarcomas. Clinicopathological heterogeneity within this tumour creates a diagnostic challenge in sorting it out from its differential diagnoses. Here we report a 42-year-old female patient presenting with a mass in the right nasal cavity for two months. With an imaging impression of a right ethmoidal polyp with a remote possibility of malignant etiology, a final diagnosis of sinonasal synovial sarcoma was made with the help of a panel of IHC antibodies. A high degree of suspicion along with a detailed work up is required to accurately diagnose synovial sarcoma in unlikely locations such as nasal cavity. Keywords: Synovial sarcoma, Nasal cavity, TLE­1, BCL2, SOX 10
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spelling doaj.art-b3b837b4e35e4a0190d47e68c5c6028a2023-01-26T17:21:28ZengADICHUNCHANAGIRI INSTITUTE OF MEDICAL SCIENCESJournal of Medical Sciences and Health2394-94812394-949X2022-12-018329229510.46347/jmsh.v8i3.22.362Sinonasal Synovial Sarcoma Masquerading as A Common Soft Tissue Tumor: A Diagnostic Challenge and Literature ReviewPranshu SaklaniShruthi N ShetageriS R Raja Parthiban Synovial sarcoma is a malignant soft tissue neoplasm which amounts to 7-10% of all sarcomas. Clinicopathological heterogeneity within this tumour creates a diagnostic challenge in sorting it out from its differential diagnoses. Here we report a 42-year-old female patient presenting with a mass in the right nasal cavity for two months. With an imaging impression of a right ethmoidal polyp with a remote possibility of malignant etiology, a final diagnosis of sinonasal synovial sarcoma was made with the help of a panel of IHC antibodies. A high degree of suspicion along with a detailed work up is required to accurately diagnose synovial sarcoma in unlikely locations such as nasal cavity. Keywords: Synovial sarcoma, Nasal cavity, TLE­1, BCL2, SOX 10https://jmsh.ac.in/articles/sinonasal-synovial-sarcoma-masquerading-as-a-common-soft-tissue-tumor-a-diagnostic-challenge-and-literature-review
spellingShingle Pranshu Saklani
Shruthi N Shetageri
S R Raja Parthiban
Sinonasal Synovial Sarcoma Masquerading as A Common Soft Tissue Tumor: A Diagnostic Challenge and Literature Review
Journal of Medical Sciences and Health
title Sinonasal Synovial Sarcoma Masquerading as A Common Soft Tissue Tumor: A Diagnostic Challenge and Literature Review
title_full Sinonasal Synovial Sarcoma Masquerading as A Common Soft Tissue Tumor: A Diagnostic Challenge and Literature Review
title_fullStr Sinonasal Synovial Sarcoma Masquerading as A Common Soft Tissue Tumor: A Diagnostic Challenge and Literature Review
title_full_unstemmed Sinonasal Synovial Sarcoma Masquerading as A Common Soft Tissue Tumor: A Diagnostic Challenge and Literature Review
title_short Sinonasal Synovial Sarcoma Masquerading as A Common Soft Tissue Tumor: A Diagnostic Challenge and Literature Review
title_sort sinonasal synovial sarcoma masquerading as a common soft tissue tumor a diagnostic challenge and literature review
url https://jmsh.ac.in/articles/sinonasal-synovial-sarcoma-masquerading-as-a-common-soft-tissue-tumor-a-diagnostic-challenge-and-literature-review
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AT shruthinshetageri sinonasalsynovialsarcomamasqueradingasacommonsofttissuetumoradiagnosticchallengeandliteraturereview
AT srrajaparthiban sinonasalsynovialsarcomamasqueradingasacommonsofttissuetumoradiagnosticchallengeandliteraturereview