Increased percentage of PD-L1+ natural killer cells predicts poor prognosis in sepsis patients: a prospective observational cohort study

Increased percentage of PD-L1+ natural killer cells predicts poor prognosis in sepsis patients: a prospective observational cohort study

Abstract Background Natural killer (NK) cells play a major role in immune tolerance after sepsis, and the programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) system mediates evasion of host immunity. The correlation between PD-L1 levels in NK cells and the prognosis of patients...

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Bibliographic Details
Main Authors: Wenqiang Jiang, Xusheng Li, Miaoyun Wen, Xiaoyu Liu, Kangrong Wang, Qiaosheng Wang, Ya Li, Maohua Zhou, Mengting Liu, Bei Hu, Hongke Zeng
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Critical Care
Subjects:
Sepsis
NK cells
PD-L1
Biomarker
Mortality
Prognosis
Online Access:http://link.springer.com/article/10.1186/s13054-020-03329-z

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