Anti-inflammatory therapy of atherosclerosis: focusing on IKKβ

Abstract Chronic low-grade inflammation has been identified as a major contributor in the development of atherosclerosis. Nuclear Factor-κappa B (NF-κB) is a critical transcription factors family of the inflammatory pathway. As a major catalytic subunit of the IKK complex, IκB kinase β (IKKβ) drives...

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Bibliographic Details
Main Authors: Jiali Gan, Lin Guo, Xiaolu Zhang, Qun Yu, Qiuyue Yang, Yilin Zhang, Wenyun Zeng, Xijuan Jiang, Maojuan Guo
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Inflammation
Subjects:
Online Access:https://doi.org/10.1186/s12950-023-00330-5