Clinical efficacy of combined therapy for perianal eczema caused by anal diseases in 160 cases

Perianal eczema is a kind of inflammatory dermatosis on the perianal skin and mucosa. The aim of the study was to evaluate the clinical efficacy of the combined therapy of medicine and operation for the perianal eczema caused by the anal diseases such as hemorrhoids, fissures and fistulas. One hundr...

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Main Authors: Zhi-Chao LIU, Jian-Gang LIU, Zhe LI, Qing SUN
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2007-01-01
Series:Indian Journal of Dermatology
Subjects:
Online Access:http://www.e-ijd.org/article.asp?issn=0019-5154;year=2007;volume=52;issue=1;spage=27;epage=29;aulast=Zhi-Chao
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author Zhi-Chao LIU
Jian-Gang LIU
Zhe LI
Qing SUN
author_facet Zhi-Chao LIU
Jian-Gang LIU
Zhe LI
Qing SUN
author_sort Zhi-Chao LIU
collection DOAJ
description Perianal eczema is a kind of inflammatory dermatosis on the perianal skin and mucosa. The aim of the study was to evaluate the clinical efficacy of the combined therapy of medicine and operation for the perianal eczema caused by the anal diseases such as hemorrhoids, fissures and fistulas. One hundred and sixty patients with perianal eczema were involved in this study. They were randomly divided into four groups and treated by different therapies for four weeks respectively. Group A (40 patients) was only treated with medicine, Group B (40 patients) only with operation, Group C (40 patients) firstly with medicine and then with operation and Group D (40 patients) firstly with operation and then with medicine. The efficacy was determined as reduction of lesion size relative to initial size. The cure rate was 22.50&#x0025;, 32.50&#x0025;, 57.50&#x0025; and 45.00&#x0025; in Group A, B, C and D, respectively. The effective rate was 40.00&#x0025;, 52.50&#x0025;, 85.00&#x0025; and 75.00&#x0025;, respectively. The efficacy was significantly different (H=20.8689, g = 3, <i> P</i> value =0.0001). The results of group comparison showed that there were significant difference between Group C and Group A, Group C and Group B, Group D and Group A (all <i> P</i> values, &lt; 0.05). It was concluded that the combined therapy of medicine and operation is optimal choice for the perianal eczema caused by the anal diseases such as hemorrhoids, fissures, and fistula. It highly improves the cure rate and efficacy rate.
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spelling doaj.art-b3bc98cbc0fe41d7b42b378b80d3a8d82022-12-22T03:51:49ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51542007-01-015212729Clinical efficacy of combined therapy for perianal eczema caused by anal diseases in 160 casesZhi-Chao LIUJian-Gang LIUZhe LIQing SUNPerianal eczema is a kind of inflammatory dermatosis on the perianal skin and mucosa. The aim of the study was to evaluate the clinical efficacy of the combined therapy of medicine and operation for the perianal eczema caused by the anal diseases such as hemorrhoids, fissures and fistulas. One hundred and sixty patients with perianal eczema were involved in this study. They were randomly divided into four groups and treated by different therapies for four weeks respectively. Group A (40 patients) was only treated with medicine, Group B (40 patients) only with operation, Group C (40 patients) firstly with medicine and then with operation and Group D (40 patients) firstly with operation and then with medicine. The efficacy was determined as reduction of lesion size relative to initial size. The cure rate was 22.50&#x0025;, 32.50&#x0025;, 57.50&#x0025; and 45.00&#x0025; in Group A, B, C and D, respectively. The effective rate was 40.00&#x0025;, 52.50&#x0025;, 85.00&#x0025; and 75.00&#x0025;, respectively. The efficacy was significantly different (H=20.8689, g = 3, <i> P</i> value =0.0001). The results of group comparison showed that there were significant difference between Group C and Group A, Group C and Group B, Group D and Group A (all <i> P</i> values, &lt; 0.05). It was concluded that the combined therapy of medicine and operation is optimal choice for the perianal eczema caused by the anal diseases such as hemorrhoids, fissures, and fistula. It highly improves the cure rate and efficacy rate.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2007;volume=52;issue=1;spage=27;epage=29;aulast=Zhi-Chao<i>Combined therapyperianal eczema</i>
spellingShingle Zhi-Chao LIU
Jian-Gang LIU
Zhe LI
Qing SUN
Clinical efficacy of combined therapy for perianal eczema caused by anal diseases in 160 cases
Indian Journal of Dermatology
<i>Combined therapy
perianal eczema</i>
title Clinical efficacy of combined therapy for perianal eczema caused by anal diseases in 160 cases
title_full Clinical efficacy of combined therapy for perianal eczema caused by anal diseases in 160 cases
title_fullStr Clinical efficacy of combined therapy for perianal eczema caused by anal diseases in 160 cases
title_full_unstemmed Clinical efficacy of combined therapy for perianal eczema caused by anal diseases in 160 cases
title_short Clinical efficacy of combined therapy for perianal eczema caused by anal diseases in 160 cases
title_sort clinical efficacy of combined therapy for perianal eczema caused by anal diseases in 160 cases
topic <i>Combined therapy
perianal eczema</i>
url http://www.e-ijd.org/article.asp?issn=0019-5154;year=2007;volume=52;issue=1;spage=27;epage=29;aulast=Zhi-Chao
work_keys_str_mv AT zhichaoliu clinicalefficacyofcombinedtherapyforperianaleczemacausedbyanaldiseasesin160cases
AT jiangangliu clinicalefficacyofcombinedtherapyforperianaleczemacausedbyanaldiseasesin160cases
AT zheli clinicalefficacyofcombinedtherapyforperianaleczemacausedbyanaldiseasesin160cases
AT qingsun clinicalefficacyofcombinedtherapyforperianaleczemacausedbyanaldiseasesin160cases