The transmission dynamic of different hepatitis B-infected individuals with the effect of hospitalization

We propose an epidemic model for the transmission of hepatitis B virus along with the classification of different infection phases and hospitalized class. We formulate the model and discuss its basic mathematical properties, e.g. existence, positivity, and biological feasibility. Exploiting the next...

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Main Authors: Tahir Khan, Gul Zaman, Muhammad Ikhlaq Chohan
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Journal of Biological Dynamics
Subjects:
Online Access:http://dx.doi.org/10.1080/17513758.2018.1500649
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author Tahir Khan
Gul Zaman
Muhammad Ikhlaq Chohan
author_facet Tahir Khan
Gul Zaman
Muhammad Ikhlaq Chohan
author_sort Tahir Khan
collection DOAJ
description We propose an epidemic model for the transmission of hepatitis B virus along with the classification of different infection phases and hospitalized class. We formulate the model and discuss its basic mathematical properties, e.g. existence, positivity, and biological feasibility. Exploiting the next generation matrix approach, we find the basic reproductive number of the model. We perform sensitivity analysis to illustrate the effect of various parameters on the transmission of the disease. We investigate stability of the equilibria of the model in terms of the basic reproduction number. Conditions for the stability of the proposed model are obtained using various approaches. Finally, we perform the numerical simulations to discuss sensitivity analysis and to support our analytical work.
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spelling doaj.art-b3bcae1780b249369653b8a6ed399b6b2022-12-22T00:22:19ZengTaylor & Francis GroupJournal of Biological Dynamics1751-37581751-37662018-01-0112161163110.1080/17513758.2018.15006491500649The transmission dynamic of different hepatitis B-infected individuals with the effect of hospitalizationTahir Khan0Gul Zaman1Muhammad Ikhlaq Chohan2University of MalakandUniversity of MalakandBuraimi University CollegeWe propose an epidemic model for the transmission of hepatitis B virus along with the classification of different infection phases and hospitalized class. We formulate the model and discuss its basic mathematical properties, e.g. existence, positivity, and biological feasibility. Exploiting the next generation matrix approach, we find the basic reproductive number of the model. We perform sensitivity analysis to illustrate the effect of various parameters on the transmission of the disease. We investigate stability of the equilibria of the model in terms of the basic reproduction number. Conditions for the stability of the proposed model are obtained using various approaches. Finally, we perform the numerical simulations to discuss sensitivity analysis and to support our analytical work.http://dx.doi.org/10.1080/17513758.2018.1500649mathematical modellingdifferent phases of hepatitis bhospitalizationbasic reproduction numbersensitivity analysisstability analysisnumerical simulation
spellingShingle Tahir Khan
Gul Zaman
Muhammad Ikhlaq Chohan
The transmission dynamic of different hepatitis B-infected individuals with the effect of hospitalization
Journal of Biological Dynamics
mathematical modelling
different phases of hepatitis b
hospitalization
basic reproduction number
sensitivity analysis
stability analysis
numerical simulation
title The transmission dynamic of different hepatitis B-infected individuals with the effect of hospitalization
title_full The transmission dynamic of different hepatitis B-infected individuals with the effect of hospitalization
title_fullStr The transmission dynamic of different hepatitis B-infected individuals with the effect of hospitalization
title_full_unstemmed The transmission dynamic of different hepatitis B-infected individuals with the effect of hospitalization
title_short The transmission dynamic of different hepatitis B-infected individuals with the effect of hospitalization
title_sort transmission dynamic of different hepatitis b infected individuals with the effect of hospitalization
topic mathematical modelling
different phases of hepatitis b
hospitalization
basic reproduction number
sensitivity analysis
stability analysis
numerical simulation
url http://dx.doi.org/10.1080/17513758.2018.1500649
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