Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report

<p>Abstract</p> <p>Rheumatoid arthritis (RA) is an autoimmune disease mediated by inflammatory processes mainly at the joints. Recently, awareness of Epstein-Barr virus (EBV)-associated T-cell lymphoproliferative disorder (T-LPD) has been heightened for its association with methotr...

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Main Authors: Suzuki Katsuya, Itoyama Shinji, Tamaru Jun-ichi, Toyozumi Yasuo, Nemoto Tomoe, Sekiguchi Yasunobu, Watanabe Reiko, Hanzawa Kyoko, Tokuhira Michihide, Kameda Hideto, Mori Shigehisa, Kizaki Masahiro
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Journal of Hematology & Oncology
Online Access:http://www.jhoonline.org/content/2/1/27
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author Suzuki Katsuya
Itoyama Shinji
Tamaru Jun-ichi
Toyozumi Yasuo
Nemoto Tomoe
Sekiguchi Yasunobu
Watanabe Reiko
Hanzawa Kyoko
Tokuhira Michihide
Kameda Hideto
Mori Shigehisa
Kizaki Masahiro
author_facet Suzuki Katsuya
Itoyama Shinji
Tamaru Jun-ichi
Toyozumi Yasuo
Nemoto Tomoe
Sekiguchi Yasunobu
Watanabe Reiko
Hanzawa Kyoko
Tokuhira Michihide
Kameda Hideto
Mori Shigehisa
Kizaki Masahiro
author_sort Suzuki Katsuya
collection DOAJ
description <p>Abstract</p> <p>Rheumatoid arthritis (RA) is an autoimmune disease mediated by inflammatory processes mainly at the joints. Recently, awareness of Epstein-Barr virus (EBV)-associated T-cell lymphoproliferative disorder (T-LPD) has been heightened for its association with methotraxate usage in RA patients. In the contrary, acute myeloid leukemia with multilineage dysplasia (AML-MLD) has never been documented to be present concomitantly with the above two conditions. In this report we present a case of an autopsy-proven co-existence of AML-MLD and EBV-associated T-LPD in a patient with RA.</p>
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spelling doaj.art-b3bf8a6a3b414643ace9ffced0ffe5b42022-12-22T03:20:50ZengBMCJournal of Hematology & Oncology1756-87222009-06-01212710.1186/1756-8722-2-27Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case reportSuzuki KatsuyaItoyama ShinjiTamaru Jun-ichiToyozumi YasuoNemoto TomoeSekiguchi YasunobuWatanabe ReikoHanzawa KyokoTokuhira MichihideKameda HidetoMori ShigehisaKizaki Masahiro<p>Abstract</p> <p>Rheumatoid arthritis (RA) is an autoimmune disease mediated by inflammatory processes mainly at the joints. Recently, awareness of Epstein-Barr virus (EBV)-associated T-cell lymphoproliferative disorder (T-LPD) has been heightened for its association with methotraxate usage in RA patients. In the contrary, acute myeloid leukemia with multilineage dysplasia (AML-MLD) has never been documented to be present concomitantly with the above two conditions. In this report we present a case of an autopsy-proven co-existence of AML-MLD and EBV-associated T-LPD in a patient with RA.</p>http://www.jhoonline.org/content/2/1/27
spellingShingle Suzuki Katsuya
Itoyama Shinji
Tamaru Jun-ichi
Toyozumi Yasuo
Nemoto Tomoe
Sekiguchi Yasunobu
Watanabe Reiko
Hanzawa Kyoko
Tokuhira Michihide
Kameda Hideto
Mori Shigehisa
Kizaki Masahiro
Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report
Journal of Hematology & Oncology
title Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report
title_full Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report
title_fullStr Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report
title_full_unstemmed Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report
title_short Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report
title_sort co existence of acute myeloid leukemia with multilineage dysplasia and epstein barr virus associated t cell lymphoproliferative disorder in a patient with rheumatoid arthritis a case report
url http://www.jhoonline.org/content/2/1/27
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