Differential Risk of Incident Fractures Depending on Intensity and Frequency of Physical Activity According to Cognitive Status: A Nationwide Longitudinal Study
Background: Previous studies have demonstrated an increased risk of fractures in subjects with various degrees of cognitive impairments. Recently, there has been growing recognition of the vital effect of physical activity (PA) on delay and prevention of fractures in older adults.Objectives: This st...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-12-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2020.572466/full |
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| author | Dong Woo Kang Sheng-Min Wang Yoo Hyun Um Hae-Ran Na Nak-Young Kim Kyungdo Han Chang Uk Lee Hyun Kook Lim |
| author_facet | Dong Woo Kang Sheng-Min Wang Yoo Hyun Um Hae-Ran Na Nak-Young Kim Kyungdo Han Chang Uk Lee Hyun Kook Lim |
| author_sort | Dong Woo Kang |
| collection | DOAJ |
| description | Background: Previous studies have demonstrated an increased risk of fractures in subjects with various degrees of cognitive impairments. Recently, there has been growing recognition of the vital effect of physical activity (PA) on delay and prevention of fractures in older adults.Objectives: This study aimed to evaluate the optimal intensity and frequency of PA needed to prevent fractures in cognitively preserved older adults (CP), participants with subjective cognitive decline (SCD), and dementia patients using a large-scale nationwide cohort study.Methods: Data from a nationwide health screening program for individuals at the transitional age of 66 years were used in this study. A total of 968,240 subjects was enrolled, followed from 2007 to 2014, and classified as CP (n = 759,874), SCD (n = 195,365), or dementia group (n = 13,001). Adjusted hazard ratios (aHRs) by demographic and known risk factors for fractures were evaluated to identify the impact of various frequency and intensity PA on the occurrence of hip, vertebral, and limb fractures.Results: In CP participants, the most noticeable reduction of hip and vertebral fracture risk was shown in those performing vigorous-intensity PA at least three times per week. In the SCD group, the risk decrement in hip and vertebral fractures was most prominent in subjects who performed multiple-intensity PAs at least three times a week regardless of intensity. In the dementia group, only high-frequency walking and high-frequency & multiple-intensity PA decreased the risk of hip fractures compared with absence of PA.Conclusion: These findings suggest a role for various PA intensity and frequency levels to prevent hip and vertebral fractures according to cognitive status. Further study is needed to validate the effects of PA intensity and frequency proposed in this study on fractures according to cognitive status. |
| first_indexed | 2024-12-22T21:05:41Z |
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| language | English |
| last_indexed | 2024-12-22T21:05:41Z |
| publishDate | 2020-12-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Medicine |
| spelling | doaj.art-b3c5bbec554d4bcb8250286d085b95022022-12-21T18:12:42ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2020-12-01710.3389/fmed.2020.572466572466Differential Risk of Incident Fractures Depending on Intensity and Frequency of Physical Activity According to Cognitive Status: A Nationwide Longitudinal StudyDong Woo Kang0Sheng-Min Wang1Yoo Hyun Um2Hae-Ran Na3Nak-Young Kim4Kyungdo Han5Chang Uk Lee6Hyun Kook Lim7Department of Psychiatry, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, South KoreaDepartment of Psychiatry, College of Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, South KoreaDepartment of Psychiatry, College of Medicine, St. Vincent's Hospital, The Catholic University of Korea, Suwon, South KoreaDepartment of Psychiatry, College of Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, South KoreaDepartment of Psychiatry, College of Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, South KoreaDepartment of Statistics and Actuarial Science, Soongsil University, Seoul, South KoreaDepartment of Psychiatry, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, South KoreaDepartment of Psychiatry, College of Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, South KoreaBackground: Previous studies have demonstrated an increased risk of fractures in subjects with various degrees of cognitive impairments. Recently, there has been growing recognition of the vital effect of physical activity (PA) on delay and prevention of fractures in older adults.Objectives: This study aimed to evaluate the optimal intensity and frequency of PA needed to prevent fractures in cognitively preserved older adults (CP), participants with subjective cognitive decline (SCD), and dementia patients using a large-scale nationwide cohort study.Methods: Data from a nationwide health screening program for individuals at the transitional age of 66 years were used in this study. A total of 968,240 subjects was enrolled, followed from 2007 to 2014, and classified as CP (n = 759,874), SCD (n = 195,365), or dementia group (n = 13,001). Adjusted hazard ratios (aHRs) by demographic and known risk factors for fractures were evaluated to identify the impact of various frequency and intensity PA on the occurrence of hip, vertebral, and limb fractures.Results: In CP participants, the most noticeable reduction of hip and vertebral fracture risk was shown in those performing vigorous-intensity PA at least three times per week. In the SCD group, the risk decrement in hip and vertebral fractures was most prominent in subjects who performed multiple-intensity PAs at least three times a week regardless of intensity. In the dementia group, only high-frequency walking and high-frequency & multiple-intensity PA decreased the risk of hip fractures compared with absence of PA.Conclusion: These findings suggest a role for various PA intensity and frequency levels to prevent hip and vertebral fractures according to cognitive status. Further study is needed to validate the effects of PA intensity and frequency proposed in this study on fractures according to cognitive status.https://www.frontiersin.org/articles/10.3389/fmed.2020.572466/fullfracturedementiasubjective cognitive declineolder adultsphysical activity |
| spellingShingle | Dong Woo Kang Sheng-Min Wang Yoo Hyun Um Hae-Ran Na Nak-Young Kim Kyungdo Han Chang Uk Lee Hyun Kook Lim Differential Risk of Incident Fractures Depending on Intensity and Frequency of Physical Activity According to Cognitive Status: A Nationwide Longitudinal Study Frontiers in Medicine fracture dementia subjective cognitive decline older adults physical activity |
| title | Differential Risk of Incident Fractures Depending on Intensity and Frequency of Physical Activity According to Cognitive Status: A Nationwide Longitudinal Study |
| title_full | Differential Risk of Incident Fractures Depending on Intensity and Frequency of Physical Activity According to Cognitive Status: A Nationwide Longitudinal Study |
| title_fullStr | Differential Risk of Incident Fractures Depending on Intensity and Frequency of Physical Activity According to Cognitive Status: A Nationwide Longitudinal Study |
| title_full_unstemmed | Differential Risk of Incident Fractures Depending on Intensity and Frequency of Physical Activity According to Cognitive Status: A Nationwide Longitudinal Study |
| title_short | Differential Risk of Incident Fractures Depending on Intensity and Frequency of Physical Activity According to Cognitive Status: A Nationwide Longitudinal Study |
| title_sort | differential risk of incident fractures depending on intensity and frequency of physical activity according to cognitive status a nationwide longitudinal study |
| topic | fracture dementia subjective cognitive decline older adults physical activity |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2020.572466/full |
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