Candida glabrata infection of the amniotic fluid with chorioamnionitis and maternal candidemia and a negative 1,3-β-D-glucan test: A case report

A case is reported of Candida glabrata microbial invasion of the amniotic cavity and maternal candidemia with a negative 1,3-β-D-glucan test. A 28-year-old singleton pregnant woman (gravida 1, para 0) presented at 18 weeks and 3 days of gestation following in vitro fertilization and embryo transfer....

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Main Authors: Michihisa Shiro, Ryo Yamamoto, Kaori Moriuchi, Keisuke Ishii
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Case Reports in Women's Health
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214911222000820
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author Michihisa Shiro
Ryo Yamamoto
Kaori Moriuchi
Keisuke Ishii
author_facet Michihisa Shiro
Ryo Yamamoto
Kaori Moriuchi
Keisuke Ishii
author_sort Michihisa Shiro
collection DOAJ
description A case is reported of Candida glabrata microbial invasion of the amniotic cavity and maternal candidemia with a negative 1,3-β-D-glucan test. A 28-year-old singleton pregnant woman (gravida 1, para 0) presented at 18 weeks and 3 days of gestation following in vitro fertilization and embryo transfer. She had suddenly experienced uterine contraction and genital bleeding with watery discharge and. After diagnosing preterm rupture of the membrane with clinical chorioamnionitis, Candida glabrata was detected both in the amniotic fluid and in the vaginal discharge; however, a test for 1,3-β-D-glucan in the maternal serum was negative. At 18 weeks and 5 days of gestation, the pregnancy was terminated after intensive counseling. On the eighth day of admission, Candida glabrata was detected in maternal blood culture. When a culture of amniotic fluid is positive for Candida glabrata, even if the 1,3-β-D-glucan test is negative, maternal candidemia should be suspected in the presence of features of clinical chorioamnionitis.
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spelling doaj.art-b3c85c52ff3c44068b8c3d1d7f1debe62022-12-22T03:54:20ZengElsevierCase Reports in Women's Health2214-91122022-10-0136e00462Candida glabrata infection of the amniotic fluid with chorioamnionitis and maternal candidemia and a negative 1,3-β-D-glucan test: A case reportMichihisa Shiro0Ryo Yamamoto1Kaori Moriuchi2Keisuke Ishii3Corresponding author at: Department of Maternal Fetal Medicine, Osaka Women's and Children's Hospital, 840 Murodo-cho, Izumi-city 594-1101, Japan.; Department of Maternal Fetal Medicine, Osaka Women's and Children's Hospital, Osaka, JapanDepartment of Maternal Fetal Medicine, Osaka Women's and Children's Hospital, Osaka, JapanDepartment of Maternal Fetal Medicine, Osaka Women's and Children's Hospital, Osaka, JapanDepartment of Maternal Fetal Medicine, Osaka Women's and Children's Hospital, Osaka, JapanA case is reported of Candida glabrata microbial invasion of the amniotic cavity and maternal candidemia with a negative 1,3-β-D-glucan test. A 28-year-old singleton pregnant woman (gravida 1, para 0) presented at 18 weeks and 3 days of gestation following in vitro fertilization and embryo transfer. She had suddenly experienced uterine contraction and genital bleeding with watery discharge and. After diagnosing preterm rupture of the membrane with clinical chorioamnionitis, Candida glabrata was detected both in the amniotic fluid and in the vaginal discharge; however, a test for 1,3-β-D-glucan in the maternal serum was negative. At 18 weeks and 5 days of gestation, the pregnancy was terminated after intensive counseling. On the eighth day of admission, Candida glabrata was detected in maternal blood culture. When a culture of amniotic fluid is positive for Candida glabrata, even if the 1,3-β-D-glucan test is negative, maternal candidemia should be suspected in the presence of features of clinical chorioamnionitis.http://www.sciencedirect.com/science/article/pii/S2214911222000820CandidemiaChorioamnionitis1,3-β-D-glucan
spellingShingle Michihisa Shiro
Ryo Yamamoto
Kaori Moriuchi
Keisuke Ishii
Candida glabrata infection of the amniotic fluid with chorioamnionitis and maternal candidemia and a negative 1,3-β-D-glucan test: A case report
Case Reports in Women's Health
Candidemia
Chorioamnionitis
1,3-β-D-glucan
title Candida glabrata infection of the amniotic fluid with chorioamnionitis and maternal candidemia and a negative 1,3-β-D-glucan test: A case report
title_full Candida glabrata infection of the amniotic fluid with chorioamnionitis and maternal candidemia and a negative 1,3-β-D-glucan test: A case report
title_fullStr Candida glabrata infection of the amniotic fluid with chorioamnionitis and maternal candidemia and a negative 1,3-β-D-glucan test: A case report
title_full_unstemmed Candida glabrata infection of the amniotic fluid with chorioamnionitis and maternal candidemia and a negative 1,3-β-D-glucan test: A case report
title_short Candida glabrata infection of the amniotic fluid with chorioamnionitis and maternal candidemia and a negative 1,3-β-D-glucan test: A case report
title_sort candida glabrata infection of the amniotic fluid with chorioamnionitis and maternal candidemia and a negative 1 3 β d glucan test a case report
topic Candidemia
Chorioamnionitis
1,3-β-D-glucan
url http://www.sciencedirect.com/science/article/pii/S2214911222000820
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