Crosstalk between hepatitis B virus X and high‐mobility group box 1 facilitates autophagy in hepatocytes

Crosstalk between hepatitis B virus X and high‐mobility group box 1 facilitates autophagy in hepatocytes

Hepatitis B virus (HBV) X (HBx) protein is a pivotal regulator of HBV‐triggered autophagy. However, the role of HBx‐induced epigenetic changes in autophagy remains largely unknown. The cytoplasmic (Cyt) high‐mobility group box 1 (HMGB1) has been identified as a positive regulator of autophagy, and i...

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Bibliographic Details
Main Authors: Sha Fu, Juan Wang, Xingwang Hu, Rong‐rong Zhou, Yongming Fu, Daolin Tang, Rui Kang, Yan Huang, Lunquan Sun, Ning Li, Xue‐Gong Fan
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:Molecular Oncology
Subjects:
acetylation
autophagy
hepatitis B virus
high‐mobility group box 1
histone deacetylases
protein protein interaction
Online Access:https://doi.org/10.1002/1878-0261.12165

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