Inhibitory Effects of Eicosapentaenoic Acid on Vascular Endothelial Growth Factor-Induced Monocyte Chemoattractant Protein-1, Interleukin-6, and Interleukin-8 in Human Vascular Endothelial Cells

Inhibitory Effects of Eicosapentaenoic Acid on Vascular Endothelial Growth Factor-Induced Monocyte Chemoattractant Protein-1, Interleukin-6, and Interleukin-8 in Human Vascular Endothelial Cells

Vascular endothelial growth factor (VEGF) induces monocyte chemoattractant protein-1 (MCP-1) and plays an important role in vascular inflammation and atherosclerosis. We investigated the mechanisms of VEGF-induced MCP-1 expression and the effects of eicosapentaenoic acid (EPA) in human umbilical vei...

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Bibliographic Details
Main Authors: Yoko Takenoshita, Akinori Tokito, Michihisa Jougasaki
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
eicosapentaenoic acid
vascular endothelial growth factor
monocyte chemoattractant protein-1
mitogen-activated protein kinase
nuclear factor-kappa B
vascular endothelial cells
Online Access:https://www.mdpi.com/1422-0067/25/5/2749

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https://www.mdpi.com/1422-0067/25/5/2749

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