The crosstalk effect between ferrous and other ions metabolism in ferroptosis for therapy of cancer

The crosstalk effect between ferrous and other ions metabolism in ferroptosis for therapy of cancer

Ferroptosis is an iron-dependent cell death process characterized by excessive accumulation of reactive oxygen species and lipid peroxidation. The elucidation of ferroptosis pathways may lead to novel cancer therapies. Current evidence suggests that the mechanism of ferroptosis can be summarized as...

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Bibliographic Details
Main Authors: Kun Ke, Li Li, Chao Lu, Qicong Zhu, Yuanyu Wang, Yiping Mou, Huiju Wang, Weiwei Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
ion metabolism
ferroptosis
glutathione metabolism
lipid peroxidation
cancer therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.916082/full

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