Management of haemorrhage in patients receiving non-vitamin-k oral anticoagulants treatment: Case report
Introduction: Management of haemorrhage depends on the severity of bleeding and associated injuries. In this paper, we present a case of bleeding patient on the anticoagulants for which there was no specific reversal agent. Aim of the study is to present the management of haemorrhage in a patient on...
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| Format: | Article |
| Language: | English |
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Serbian Medical Society, Department of Emergency Medicine, Belgrade
2022-01-01
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| Series: | ABC: časopis urgentne medicine |
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| Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/1451-1053/2022/1451-10532202007R.pdf |
| _version_ | 1797367034234798080 |
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| author | Rangelov-Kulezić Jasmina Vragolić-Milošević Vanja Tadić Milorad Popović Radmila |
| author_facet | Rangelov-Kulezić Jasmina Vragolić-Milošević Vanja Tadić Milorad Popović Radmila |
| author_sort | Rangelov-Kulezić Jasmina |
| collection | DOAJ |
| description | Introduction: Management of haemorrhage depends on the severity of bleeding and associated injuries. In this paper, we present a case of bleeding patient on the anticoagulants for which there was no specific reversal agent. Aim of the study is to present the management of haemorrhage in a patient on anticoagulant therapy in the General Hospital in Loznica, Serbia. Material and methods: Overview of hospital documentation and physician's reports. Case report: In the abscence of a specific reversal agents and laboratory tests, management of haemorrhage included methods of mechanical/surgical haemorrhage control, application of antifibrinolitics and administration of blood products, such as fresh frozen plasma (FFP), combined with forced diuresis and 7-day clinial follow-up period. NOAC treatment was suspended until the complete stopping of bleeding. After the bleeding was stopped, non-vitamin-K oral anticoagulants (NOAC) treatment was resumed with lowered dosis. Conclusion: In the abscence of specific reversal agents, reversion of NOAC effects is possible in minor haemorrhage. Patients with major haemorrhage should be treated with available specific reversal agents and/or prothrombin complex concentrate (PCC). However, this type of therapy is currrently available only in the terciary health care intitutions. |
| first_indexed | 2024-03-08T17:12:08Z |
| format | Article |
| id | doaj.art-b3ce0911204c4cb986175df37d9a3cee |
| institution | Directory Open Access Journal |
| issn | 1451-1053 2560-3922 |
| language | English |
| last_indexed | 2024-03-08T17:12:08Z |
| publishDate | 2022-01-01 |
| publisher | Serbian Medical Society, Department of Emergency Medicine, Belgrade |
| record_format | Article |
| series | ABC: časopis urgentne medicine |
| spelling | doaj.art-b3ce0911204c4cb986175df37d9a3cee2024-01-03T21:17:54ZengSerbian Medical Society, Department of Emergency Medicine, BelgradeABC: časopis urgentne medicine1451-10532560-39222022-01-0122271010.5937/abc2202007K1451-10532202007RManagement of haemorrhage in patients receiving non-vitamin-k oral anticoagulants treatment: Case reportRangelov-Kulezić Jasmina0Vragolić-Milošević Vanja1Tadić Milorad2Popović Radmila3Opšta bolnica Loznica, Bolnička banka krvi, Loznica, SerbiaOpšta bolnica Loznica, Interno odeljenje, Loznica, SerbiaOpšta bolnica Loznica, Sluz ba prijema i zbrinjavanja urgentnih štanja, Loznica, SerbiaOpšta bolnica Loznica, Bolnička banka krvi, Loznica, SerbiaIntroduction: Management of haemorrhage depends on the severity of bleeding and associated injuries. In this paper, we present a case of bleeding patient on the anticoagulants for which there was no specific reversal agent. Aim of the study is to present the management of haemorrhage in a patient on anticoagulant therapy in the General Hospital in Loznica, Serbia. Material and methods: Overview of hospital documentation and physician's reports. Case report: In the abscence of a specific reversal agents and laboratory tests, management of haemorrhage included methods of mechanical/surgical haemorrhage control, application of antifibrinolitics and administration of blood products, such as fresh frozen plasma (FFP), combined with forced diuresis and 7-day clinial follow-up period. NOAC treatment was suspended until the complete stopping of bleeding. After the bleeding was stopped, non-vitamin-K oral anticoagulants (NOAC) treatment was resumed with lowered dosis. Conclusion: In the abscence of specific reversal agents, reversion of NOAC effects is possible in minor haemorrhage. Patients with major haemorrhage should be treated with available specific reversal agents and/or prothrombin complex concentrate (PCC). However, this type of therapy is currrently available only in the terciary health care intitutions.https://scindeks-clanci.ceon.rs/data/pdf/1451-1053/2022/1451-10532202007R.pdforal anticoagulantsbleedingriskantidotelaboratory monitoring |
| spellingShingle | Rangelov-Kulezić Jasmina Vragolić-Milošević Vanja Tadić Milorad Popović Radmila Management of haemorrhage in patients receiving non-vitamin-k oral anticoagulants treatment: Case report ABC: časopis urgentne medicine oral anticoagulants bleeding risk antidote laboratory monitoring |
| title | Management of haemorrhage in patients receiving non-vitamin-k oral anticoagulants treatment: Case report |
| title_full | Management of haemorrhage in patients receiving non-vitamin-k oral anticoagulants treatment: Case report |
| title_fullStr | Management of haemorrhage in patients receiving non-vitamin-k oral anticoagulants treatment: Case report |
| title_full_unstemmed | Management of haemorrhage in patients receiving non-vitamin-k oral anticoagulants treatment: Case report |
| title_short | Management of haemorrhage in patients receiving non-vitamin-k oral anticoagulants treatment: Case report |
| title_sort | management of haemorrhage in patients receiving non vitamin k oral anticoagulants treatment case report |
| topic | oral anticoagulants bleeding risk antidote laboratory monitoring |
| url | https://scindeks-clanci.ceon.rs/data/pdf/1451-1053/2022/1451-10532202007R.pdf |
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