Capsaicin-Induced Glutamate Release Is Implicated in Nociceptive Processing Through Activation of Ionotropic Glutamate Receptors and Group I Metabotropic Glutamate Receptor in Primary Afferent Fibers
Glutamate (Glu) is the major excitatory neurotransmitter in the central nervous system. The role of peripheral Glu and Glu receptors (GluRs) in nociceptive transmission is, however, still unclear. In the present study, we examined Glu levels released in the subcutaneous perfusate of the rat hind ins...
Main Authors: | You-Hong Jin, Fumiko Yamaki, Motohide Takemura, Yuichi Koike, Akira Furuyama, Norifumi Yonehara |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2009-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319312782 |
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