BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate

BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate

Vascular calcification associated with high plasma phosphate (Pi) level is a frequent complication of hyperglycemia, diabetes mellitus, and chronic kidney disease. BGP-15 is an emerging anti-diabetic drug candidate. This study was aimed to explore whether BGP-15 inhibits high Pi-induced calcificatio...

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Bibliographic Details
Main Authors: Annamária Nagy, Dávid Pethő, Rudolf Gesztelyi, Béla Juhász, György Balla, Zoltán Szilvássy, József Balla, Tamás Gáll
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
BGP-15
vascular smooth muscle cell
vascular calcification
high glucose
diabetes mellitus
Online Access:https://www.mdpi.com/1422-0067/22/17/9263

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