The fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cells
Basolateral recycling and transcytotic pathways in epithelial cells are defined by specific markers, however the apical recycling pathway is poorly understood. Perez Bay et al. show that Megalin is a marker for this pathway, which intersects with the other routes in shared perinuclear recycling endo...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2016-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms11550 |
| _version_ | 1819202718314528768 |
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| author | Andres E. Perez Bay Ryan Schreiner Ignacio Benedicto Maria Paz Marzolo Jason Banfelder Alan M. Weinstein Enrique J. Rodriguez-Boulan |
| author_facet | Andres E. Perez Bay Ryan Schreiner Ignacio Benedicto Maria Paz Marzolo Jason Banfelder Alan M. Weinstein Enrique J. Rodriguez-Boulan |
| author_sort | Andres E. Perez Bay |
| collection | DOAJ |
| description | Basolateral recycling and transcytotic pathways in epithelial cells are defined by specific markers, however the apical recycling pathway is poorly understood. Perez Bay et al. show that Megalin is a marker for this pathway, which intersects with the other routes in shared perinuclear recycling endosomes. |
| first_indexed | 2024-12-23T04:08:28Z |
| format | Article |
| id | doaj.art-b3cf9e8370044b469e29147b973a3690 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-23T04:08:28Z |
| publishDate | 2016-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-b3cf9e8370044b469e29147b973a36902022-12-21T18:00:34ZengNature PortfolioNature Communications2041-17232016-05-017111510.1038/ncomms11550The fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cellsAndres E. Perez Bay0Ryan Schreiner1Ignacio Benedicto2Maria Paz Marzolo3Jason Banfelder4Alan M. Weinstein5Enrique J. Rodriguez-Boulan6Department of Ophthalmology, Margaret Dyson Vision Research Institute, Weill Medical College of Cornell UniversityDepartment of Ophthalmology, Margaret Dyson Vision Research Institute, Weill Medical College of Cornell UniversityDepartment of Ophthalmology, Margaret Dyson Vision Research Institute, Weill Medical College of Cornell UniversityDepartamento de Biología Celular y Molecular, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de ChileDepartment of Physiology and Biophysics, Weill Medical College of Cornell UniversityDepartment of Physiology and Biophysics, Weill Medical College of Cornell UniversityDepartment of Ophthalmology, Margaret Dyson Vision Research Institute, Weill Medical College of Cornell UniversityBasolateral recycling and transcytotic pathways in epithelial cells are defined by specific markers, however the apical recycling pathway is poorly understood. Perez Bay et al. show that Megalin is a marker for this pathway, which intersects with the other routes in shared perinuclear recycling endosomes.https://doi.org/10.1038/ncomms11550 |
| spellingShingle | Andres E. Perez Bay Ryan Schreiner Ignacio Benedicto Maria Paz Marzolo Jason Banfelder Alan M. Weinstein Enrique J. Rodriguez-Boulan The fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cells Nature Communications |
| title | The fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cells |
| title_full | The fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cells |
| title_fullStr | The fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cells |
| title_full_unstemmed | The fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cells |
| title_short | The fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cells |
| title_sort | fast recycling receptor megalin defines the apical recycling pathway of epithelial cells |
| url | https://doi.org/10.1038/ncomms11550 |
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