Effects of Dietary β-Mannanase Supplementation on Growth Performance, Apparent Total Tract Digestibility, Intestinal Integrity, and Immune Responses in Weaning Pigs
The experiment aimed to investigate the effects of dietary β-mannanase supplementation on growth performance, apparent total tract digestibility (ATTD) of nutrients, intestinal integrity, and the immunological and oxidative stress parameters in weaning pigs. A total of 64 newly weaning pigs (initial...
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MDPI AG
2020-04-01
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| Online Access: | https://www.mdpi.com/2076-2615/10/4/703 |
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| author | Jae-Cheol Jang Kwang Ho Kim Young Dal Jang Yoo Yong Kim |
| author_facet | Jae-Cheol Jang Kwang Ho Kim Young Dal Jang Yoo Yong Kim |
| author_sort | Jae-Cheol Jang |
| collection | DOAJ |
| description | The experiment aimed to investigate the effects of dietary β-mannanase supplementation on growth performance, apparent total tract digestibility (ATTD) of nutrients, intestinal integrity, and the immunological and oxidative stress parameters in weaning pigs. A total of 64 newly weaning pigs (initial body weight: 6.96 ± 0.70 kg) were allotted to two dietary treatments in eight replicates per treatment with four pigs per pen based on body weight and sex. Dietary treatments were 1.) CON (control: corn-soybean meal based basal diet) and 2.) β-mannanase (basal diet +0.06% β-mannanase). The β-mannanase supplementation did not affect growth performance, concentrations of acute phase protein, superoxide dismutase and glutathione peroxidase. However, the pigs fed the β-mannanase-supplemented diet had greater ATTD of ether extract, jejunum villus height, and villus height-to-crypt depth ratio, and lower crypt depth compared with those fed the CON diet (<i>p</i> < 0.05). The pigs fed the β-mannanase-supplemented diet tended to have the lower count of <i>E. coli</i> in cecum than those fed the CON diet (<i>p</i> = 0.08). In conclusion, dietary β-mannanase supplementation did not affect growth performance, immune response and oxidative stress of weaning pigs, whereas it increased fat digestibility and had positive effects on intestinal integrity and cecum microflora by reducing the count of <i>E.coli</i>. |
| first_indexed | 2024-03-10T20:24:27Z |
| format | Article |
| id | doaj.art-b3d05da1f9d64822868153ba279c2214 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T20:24:27Z |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-b3d05da1f9d64822868153ba279c22142023-11-19T21:56:17ZengMDPI AGAnimals2076-26152020-04-0110470310.3390/ani10040703Effects of Dietary β-Mannanase Supplementation on Growth Performance, Apparent Total Tract Digestibility, Intestinal Integrity, and Immune Responses in Weaning PigsJae-Cheol Jang0Kwang Ho Kim1Young Dal Jang2Yoo Yong Kim3Department of Agricultural Biotechnology, and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, KoreaDepartment of Agricultural Biotechnology, and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, KoreaDepartment of Agricultural Biotechnology, and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, KoreaDepartment of Agricultural Biotechnology, and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, KoreaThe experiment aimed to investigate the effects of dietary β-mannanase supplementation on growth performance, apparent total tract digestibility (ATTD) of nutrients, intestinal integrity, and the immunological and oxidative stress parameters in weaning pigs. A total of 64 newly weaning pigs (initial body weight: 6.96 ± 0.70 kg) were allotted to two dietary treatments in eight replicates per treatment with four pigs per pen based on body weight and sex. Dietary treatments were 1.) CON (control: corn-soybean meal based basal diet) and 2.) β-mannanase (basal diet +0.06% β-mannanase). The β-mannanase supplementation did not affect growth performance, concentrations of acute phase protein, superoxide dismutase and glutathione peroxidase. However, the pigs fed the β-mannanase-supplemented diet had greater ATTD of ether extract, jejunum villus height, and villus height-to-crypt depth ratio, and lower crypt depth compared with those fed the CON diet (<i>p</i> < 0.05). The pigs fed the β-mannanase-supplemented diet tended to have the lower count of <i>E. coli</i> in cecum than those fed the CON diet (<i>p</i> = 0.08). In conclusion, dietary β-mannanase supplementation did not affect growth performance, immune response and oxidative stress of weaning pigs, whereas it increased fat digestibility and had positive effects on intestinal integrity and cecum microflora by reducing the count of <i>E.coli</i>.https://www.mdpi.com/2076-2615/10/4/703acute phase proteinβ-mannanasegrowth performanceintestinal morphologyoxidative stressapparent total tract digestibility |
| spellingShingle | Jae-Cheol Jang Kwang Ho Kim Young Dal Jang Yoo Yong Kim Effects of Dietary β-Mannanase Supplementation on Growth Performance, Apparent Total Tract Digestibility, Intestinal Integrity, and Immune Responses in Weaning Pigs Animals acute phase protein β-mannanase growth performance intestinal morphology oxidative stress apparent total tract digestibility |
| title | Effects of Dietary β-Mannanase Supplementation on Growth Performance, Apparent Total Tract Digestibility, Intestinal Integrity, and Immune Responses in Weaning Pigs |
| title_full | Effects of Dietary β-Mannanase Supplementation on Growth Performance, Apparent Total Tract Digestibility, Intestinal Integrity, and Immune Responses in Weaning Pigs |
| title_fullStr | Effects of Dietary β-Mannanase Supplementation on Growth Performance, Apparent Total Tract Digestibility, Intestinal Integrity, and Immune Responses in Weaning Pigs |
| title_full_unstemmed | Effects of Dietary β-Mannanase Supplementation on Growth Performance, Apparent Total Tract Digestibility, Intestinal Integrity, and Immune Responses in Weaning Pigs |
| title_short | Effects of Dietary β-Mannanase Supplementation on Growth Performance, Apparent Total Tract Digestibility, Intestinal Integrity, and Immune Responses in Weaning Pigs |
| title_sort | effects of dietary β mannanase supplementation on growth performance apparent total tract digestibility intestinal integrity and immune responses in weaning pigs |
| topic | acute phase protein β-mannanase growth performance intestinal morphology oxidative stress apparent total tract digestibility |
| url | https://www.mdpi.com/2076-2615/10/4/703 |
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