Drug correction of intestinal dyskinesias
Selective myotropic spasmolytics are the most effective modern correction means for pain at irritable bowel syndrome. Currently various drugs of mebeverine hydrochloride are represented in the domestic market, the dosage of the active substance in which is identical but they are produced by various...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Remedium Group LLC
2016-12-01
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| Series: | Медицинский совет |
| Subjects: | |
| Online Access: | https://www.med-sovet.pro/jour/article/view/1470 |
| _version_ | 1797841451693899776 |
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| author | M. A. Butov E. M. Shurpo P. S. Kuznetsov I. A. Zagravskaya |
| author_facet | M. A. Butov E. M. Shurpo P. S. Kuznetsov I. A. Zagravskaya |
| author_sort | M. A. Butov |
| collection | DOAJ |
| description | Selective myotropic spasmolytics are the most effective modern correction means for pain at irritable bowel syndrome. Currently various drugs of mebeverine hydrochloride are represented in the domestic market, the dosage of the active substance in which is identical but they are produced by various technologies. We established that in patients with the irritable bowel syndrome administration of the drug Niaspam (Sun Pharmaceutical Industries Ltd.) at standard dosages for 2 weeks showed high effectiveness in arresting pain syndrome and intestinal dyskinesias. Niaspam statistically reliably reduces the relative intensity of intestinal contractions, normalizes the contraction rythmicity but effective predominantly in lower parts of the gastrointestinal tract. Peculiarities of the production technology allow gradual mebeverine release from the capsule, which is extremely important in therapy of intestinal dyskinesias. |
| first_indexed | 2024-04-09T16:31:04Z |
| format | Article |
| id | doaj.art-b3d0bfc4b07b4a8ebd50cd05c4f8b2e4 |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:31:04Z |
| publishDate | 2016-12-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-b3d0bfc4b07b4a8ebd50cd05c4f8b2e42023-04-23T06:57:06ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902016-12-01014969910.21518/2079-701X-2016-14-96-991466Drug correction of intestinal dyskinesiasM. A. Butov0E. M. Shurpo1P. S. Kuznetsov2I. A. Zagravskaya3SBEI HPE Pavlov Ryazan State Medical University of the Ministry of Health of the Russian FederationSBEI HPE Pavlov Ryazan State Medical University of the Ministry of Health of the Russian FederationSBEI HPE Pavlov Ryazan State Medical University of the Ministry of Health of the Russian FederationSBEI HPE Pavlov Ryazan State Medical University of the Ministry of Health of the Russian FederationSelective myotropic spasmolytics are the most effective modern correction means for pain at irritable bowel syndrome. Currently various drugs of mebeverine hydrochloride are represented in the domestic market, the dosage of the active substance in which is identical but they are produced by various technologies. We established that in patients with the irritable bowel syndrome administration of the drug Niaspam (Sun Pharmaceutical Industries Ltd.) at standard dosages for 2 weeks showed high effectiveness in arresting pain syndrome and intestinal dyskinesias. Niaspam statistically reliably reduces the relative intensity of intestinal contractions, normalizes the contraction rythmicity but effective predominantly in lower parts of the gastrointestinal tract. Peculiarities of the production technology allow gradual mebeverine release from the capsule, which is extremely important in therapy of intestinal dyskinesias.https://www.med-sovet.pro/jour/article/view/1470mebeverine hydrochlorideintestinal dyskinesiasirritable bowel syndrome |
| spellingShingle | M. A. Butov E. M. Shurpo P. S. Kuznetsov I. A. Zagravskaya Drug correction of intestinal dyskinesias Медицинский совет mebeverine hydrochloride intestinal dyskinesias irritable bowel syndrome |
| title | Drug correction of intestinal dyskinesias |
| title_full | Drug correction of intestinal dyskinesias |
| title_fullStr | Drug correction of intestinal dyskinesias |
| title_full_unstemmed | Drug correction of intestinal dyskinesias |
| title_short | Drug correction of intestinal dyskinesias |
| title_sort | drug correction of intestinal dyskinesias |
| topic | mebeverine hydrochloride intestinal dyskinesias irritable bowel syndrome |
| url | https://www.med-sovet.pro/jour/article/view/1470 |
| work_keys_str_mv | AT mabutov drugcorrectionofintestinaldyskinesias AT emshurpo drugcorrectionofintestinaldyskinesias AT pskuznetsov drugcorrectionofintestinaldyskinesias AT iazagravskaya drugcorrectionofintestinaldyskinesias |