Crystal structure of the human SUV39H1 chromodomain and its recognition of histone H3K9me2/3.
SUV39H1, the first identified histone lysine methyltransferase in human, is involved in chromatin modification and gene regulation. SUV39H1 contains a chromodomain in its N-terminus, which potentially plays a role in methyl-lysine recognition and SUV39H1 targeting. In this study, the structure of th...
| Հիմնական հեղինակներ: | , , , , , , , , , , , , |
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| Ձևաչափ: | Հոդված |
| Լեզու: | English |
| Հրապարակվել է: |
Public Library of Science (PLoS)
2012-01-01
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| Շարք: | PLoS ONE |
| Առցանց հասանելիություն: | http://europepmc.org/articles/PMC3532415?pdf=render |