High sodium chloride affects BMP-7 and 1α-hydroxylase levels through NCC and CLC-5 in NRK-52E cells

High sodium chloride affects BMP-7 and 1α-hydroxylase levels through NCC and CLC-5 in NRK-52E cells

A diet high in sodium chloride (NaCl) can affect renal function damage and increase urinary calcium excretion, leading to bone loss. in renal tubules, Na-Cl co-transporter (NCC) and chloride channel 5 (CLC-5) are involved in regulating urinary calcium excretion. In addition, some cytokines, such as...

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Bibliographic Details
Main Authors: Shu Mo, Yan Cui, Kehuan Sun, Haixia Wang, Xunqian Peng, Ling Ou, Xiaojun Lei, Mengtian Huang, Wenhui Mei, Ling Xin, Haibing He, Bojia Peng, Ya Tian, Panpan Wang, Xiaoyun Li, Ronghua Zhang, Xiaofeng Zhu
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Bone mineral density
CLC-5
NCC
NRK-52E cell
Sodium chloride
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321008745

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