MHCII-peptide presentation: an assessment of the state-of-the-art prediction methods

MHCII-peptide presentation: an assessment of the state-of-the-art prediction methods

Major histocompatibility complex Class II (MHCII) proteins initiate and regulate immune responses by presentation of antigenic peptides to CD4+ T-cells and self-restriction. The interactions between MHCII and peptides determine the specificity of the immune response and are crucial in immunotherapy...

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Bibliographic Details
Main Authors: Yaqing Yang, Zhonghui Wei, Gabriel Cia, Xixi Song, Fabrizio Pucci, Marianne Rooman, Fuzhong Xue, Qingzhen Hou
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
MHCII
peptide binding prediction
immunology
bioinformatics
webserver
machine learning
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1293706/full

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