Stillbirth and Preterm Birth During Lockdown Periods in 5 Waves of COVID-19 Pandemic in Northern Iran: A Region-Wide Cohort Study in Mazandaran Province
Introduction Conflicting reports for preterm birth and stillbirth during the lockdown imposed during the COVID-19 pandemic have emerged. Most of the studies are related to the initial waves of the pandemic. Objectives This study aims to evaluate changes in preterm birth and stillbirth rates during v...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2023-06-01
|
| Series: | Health Services Research & Managerial Epidemiology |
| Online Access: | https://doi.org/10.1177/23333928231180561 |
| _version_ | 1797800932304486400 |
|---|---|
| author | Roya Farhadi Hanieh Noori Vajiheh GhaffariSaravi Mahmood Moosazadeh |
| author_facet | Roya Farhadi Hanieh Noori Vajiheh GhaffariSaravi Mahmood Moosazadeh |
| author_sort | Roya Farhadi |
| collection | DOAJ |
| description | Introduction Conflicting reports for preterm birth and stillbirth during the lockdown imposed during the COVID-19 pandemic have emerged. Most of the studies are related to the initial waves of the pandemic. Objectives This study aims to evaluate changes in preterm birth and stillbirth rates during various waves of COVID-19 in northern Iran. Methods This is a retrospective cohort study to evaluate preterm birth and stillbirth rate based on weight distribution per 1000 live births during lockdown periods in 5 peaks of the COVID-19 pandemic using the regional data registration system at Mazandaran University of Medical Sciences in northern Iran. We compared these rates with the corresponding months 4 years before the pandemic. The odds ratio for the primary outcome was estimated by logistic regression. Results We observed an overall increased rate of preterm birth during the pandemic compared to the pre-pandemic period (4.7% vs 2.8%, P < .001). The overall stillbirth rate increased during the COVID-19 pandemic compared to the pre-pandemic period (7.48/1000 vs 5.41/1000, odds ratio: 1.38 [1.21-1.57]). This increase in the rate of stillbirth was significantly observed in the fifth wave of the COVID-19 pandemic ( P < .001). Conclusion Our study showed that adverse pregnancy outcomes increased during lockdown periods of a global pandemic. Further studies from geographically diverse regions to evaluate different behavior changes during pregnancy and access to prenatal services, and its impact on pregnancy outcomes is recommended. |
| first_indexed | 2024-03-13T04:42:36Z |
| format | Article |
| id | doaj.art-b3e3e00bd869412790e3e7100673d7dc |
| institution | Directory Open Access Journal |
| issn | 2333-3928 |
| language | English |
| last_indexed | 2024-03-13T04:42:36Z |
| publishDate | 2023-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Health Services Research & Managerial Epidemiology |
| spelling | doaj.art-b3e3e00bd869412790e3e7100673d7dc2023-06-19T04:33:19ZengSAGE PublishingHealth Services Research & Managerial Epidemiology2333-39282023-06-011010.1177/23333928231180561Stillbirth and Preterm Birth During Lockdown Periods in 5 Waves of COVID-19 Pandemic in Northern Iran: A Region-Wide Cohort Study in Mazandaran ProvinceRoya Farhadi0Hanieh Noori1Vajiheh GhaffariSaravi2Mahmood Moosazadeh3 Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, , Sari, Iran Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, , Sari, Iran Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, , Sari, Iran Health Sciences Research Center, , Sari, IranIntroduction Conflicting reports for preterm birth and stillbirth during the lockdown imposed during the COVID-19 pandemic have emerged. Most of the studies are related to the initial waves of the pandemic. Objectives This study aims to evaluate changes in preterm birth and stillbirth rates during various waves of COVID-19 in northern Iran. Methods This is a retrospective cohort study to evaluate preterm birth and stillbirth rate based on weight distribution per 1000 live births during lockdown periods in 5 peaks of the COVID-19 pandemic using the regional data registration system at Mazandaran University of Medical Sciences in northern Iran. We compared these rates with the corresponding months 4 years before the pandemic. The odds ratio for the primary outcome was estimated by logistic regression. Results We observed an overall increased rate of preterm birth during the pandemic compared to the pre-pandemic period (4.7% vs 2.8%, P < .001). The overall stillbirth rate increased during the COVID-19 pandemic compared to the pre-pandemic period (7.48/1000 vs 5.41/1000, odds ratio: 1.38 [1.21-1.57]). This increase in the rate of stillbirth was significantly observed in the fifth wave of the COVID-19 pandemic ( P < .001). Conclusion Our study showed that adverse pregnancy outcomes increased during lockdown periods of a global pandemic. Further studies from geographically diverse regions to evaluate different behavior changes during pregnancy and access to prenatal services, and its impact on pregnancy outcomes is recommended.https://doi.org/10.1177/23333928231180561 |
| spellingShingle | Roya Farhadi Hanieh Noori Vajiheh GhaffariSaravi Mahmood Moosazadeh Stillbirth and Preterm Birth During Lockdown Periods in 5 Waves of COVID-19 Pandemic in Northern Iran: A Region-Wide Cohort Study in Mazandaran Province Health Services Research & Managerial Epidemiology |
| title | Stillbirth and Preterm Birth During Lockdown Periods in 5 Waves of COVID-19 Pandemic in Northern Iran: A Region-Wide Cohort Study in Mazandaran Province |
| title_full | Stillbirth and Preterm Birth During Lockdown Periods in 5 Waves of COVID-19 Pandemic in Northern Iran: A Region-Wide Cohort Study in Mazandaran Province |
| title_fullStr | Stillbirth and Preterm Birth During Lockdown Periods in 5 Waves of COVID-19 Pandemic in Northern Iran: A Region-Wide Cohort Study in Mazandaran Province |
| title_full_unstemmed | Stillbirth and Preterm Birth During Lockdown Periods in 5 Waves of COVID-19 Pandemic in Northern Iran: A Region-Wide Cohort Study in Mazandaran Province |
| title_short | Stillbirth and Preterm Birth During Lockdown Periods in 5 Waves of COVID-19 Pandemic in Northern Iran: A Region-Wide Cohort Study in Mazandaran Province |
| title_sort | stillbirth and preterm birth during lockdown periods in 5 waves of covid 19 pandemic in northern iran a region wide cohort study in mazandaran province |
| url | https://doi.org/10.1177/23333928231180561 |
| work_keys_str_mv | AT royafarhadi stillbirthandpretermbirthduringlockdownperiodsin5wavesofcovid19pandemicinnortherniranaregionwidecohortstudyinmazandaranprovince AT haniehnoori stillbirthandpretermbirthduringlockdownperiodsin5wavesofcovid19pandemicinnortherniranaregionwidecohortstudyinmazandaranprovince AT vajihehghaffarisaravi stillbirthandpretermbirthduringlockdownperiodsin5wavesofcovid19pandemicinnortherniranaregionwidecohortstudyinmazandaranprovince AT mahmoodmoosazadeh stillbirthandpretermbirthduringlockdownperiodsin5wavesofcovid19pandemicinnortherniranaregionwidecohortstudyinmazandaranprovince |