Expression of SGLT1 in Human Hearts and Impairment of Cardiac Glucose Uptake by Phlorizin during Ischemia-Reperfusion Injury in Mice.

Sodium-glucose cotransporter 1 (SGLT1) is thought to be expressed in the heart as the dominant isoform of cardiac SGLT, although more information is required to delineate the subtypes of SGLTs in human hearts. Moreover, the functional role of SGLTs in the heart remains to be fully elucidated. We her...

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Main Authors: Yusuke Kashiwagi, Tomohisa Nagoshi, Takuya Yoshino, Toshikazu D Tanaka, Keiichi Ito, Tohru Harada, Hiroyuki Takahashi, Masahiro Ikegami, Ryuko Anzawa, Michihiro Yoshimura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4486720?pdf=render