Effect of hyperglycaemia on outcome of critically ill patients with and without diabetes mellitus admitted to medical intensive care unit
Background: Hyperglycaemia among critically ill patients is associated with nosocomial infections, multi-organ dysfunction and prolonged hospitalisation. Sparse data are available regarding the effect of hyperglycaemia on mortality in medical intensive care unit (MICU) patients in India. Methods: A...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Journal of Clinical and Scientific Research |
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| Online Access: | http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2022;volume=11;issue=3;spage=157;epage=161;aulast=Lakshmi |
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| author | T Sowjanya Lakshmi D T Katyarmal Sameeraja Vaddera Suresh Vaikkakara K V S. Sarma |
| author_facet | T Sowjanya Lakshmi D T Katyarmal Sameeraja Vaddera Suresh Vaikkakara K V S. Sarma |
| author_sort | T Sowjanya Lakshmi |
| collection | DOAJ |
| description | Background: Hyperglycaemia among critically ill patients is associated with nosocomial infections, multi-organ dysfunction and prolonged hospitalisation. Sparse data are available regarding the effect of hyperglycaemia on mortality in medical intensive care unit (MICU) patients in India.
Methods: A prospective study was conducted in MICU at a tertiary teaching hospital in Southern India during the period of March 2018–June 2019. Patients were classified as having/not having diabetes mellitus. Blood glucose was monitored in all patients with. Age, severity of critical illness, comorbidities and laboratory variables were recorded. The association of hyperglycaemia with mortality was studied.
Results: Patients with diabetes mellitus were older, had more number of comorbidities like hypertension, coronary artery disease compared to those without diabetes mellitus. On logistic regression analysis mean blood glucose did not emerge as an independent determinant of mortality in patients with and without diabetes mellitus. The acute physiology and chronic health evaluation II (APACHE II) score was found to be an independent determinant of mortality in patient with (P = 0.0001) and without (P = 0.0001) diabetes mellitus.
Conclusion: Our observations suggest that in critically ill patients with or without diabetes mellitus admitted to MICU, hyperglycaemia was not a predictor of mortality. |
| first_indexed | 2024-04-13T19:35:48Z |
| format | Article |
| id | doaj.art-b3eaf4ca7c894a0db466607f8dc4bbb0 |
| institution | Directory Open Access Journal |
| issn | 2277-5706 2277-8357 |
| language | English |
| last_indexed | 2024-04-13T19:35:48Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Clinical and Scientific Research |
| spelling | doaj.art-b3eaf4ca7c894a0db466607f8dc4bbb02022-12-22T02:33:03ZengWolters Kluwer Medknow PublicationsJournal of Clinical and Scientific Research2277-57062277-83572022-01-0111315716110.4103/jcsr.jcsr_60_21Effect of hyperglycaemia on outcome of critically ill patients with and without diabetes mellitus admitted to medical intensive care unitT Sowjanya LakshmiD T KatyarmalSameeraja VadderaSuresh VaikkakaraK V S. SarmaBackground: Hyperglycaemia among critically ill patients is associated with nosocomial infections, multi-organ dysfunction and prolonged hospitalisation. Sparse data are available regarding the effect of hyperglycaemia on mortality in medical intensive care unit (MICU) patients in India. Methods: A prospective study was conducted in MICU at a tertiary teaching hospital in Southern India during the period of March 2018–June 2019. Patients were classified as having/not having diabetes mellitus. Blood glucose was monitored in all patients with. Age, severity of critical illness, comorbidities and laboratory variables were recorded. The association of hyperglycaemia with mortality was studied. Results: Patients with diabetes mellitus were older, had more number of comorbidities like hypertension, coronary artery disease compared to those without diabetes mellitus. On logistic regression analysis mean blood glucose did not emerge as an independent determinant of mortality in patients with and without diabetes mellitus. The acute physiology and chronic health evaluation II (APACHE II) score was found to be an independent determinant of mortality in patient with (P = 0.0001) and without (P = 0.0001) diabetes mellitus. Conclusion: Our observations suggest that in critically ill patients with or without diabetes mellitus admitted to MICU, hyperglycaemia was not a predictor of mortality.http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2022;volume=11;issue=3;spage=157;epage=161;aulast=Lakshmicritically illhyperglycaemiamortality |
| spellingShingle | T Sowjanya Lakshmi D T Katyarmal Sameeraja Vaddera Suresh Vaikkakara K V S. Sarma Effect of hyperglycaemia on outcome of critically ill patients with and without diabetes mellitus admitted to medical intensive care unit Journal of Clinical and Scientific Research critically ill hyperglycaemia mortality |
| title | Effect of hyperglycaemia on outcome of critically ill patients with and without diabetes mellitus admitted to medical intensive care unit |
| title_full | Effect of hyperglycaemia on outcome of critically ill patients with and without diabetes mellitus admitted to medical intensive care unit |
| title_fullStr | Effect of hyperglycaemia on outcome of critically ill patients with and without diabetes mellitus admitted to medical intensive care unit |
| title_full_unstemmed | Effect of hyperglycaemia on outcome of critically ill patients with and without diabetes mellitus admitted to medical intensive care unit |
| title_short | Effect of hyperglycaemia on outcome of critically ill patients with and without diabetes mellitus admitted to medical intensive care unit |
| title_sort | effect of hyperglycaemia on outcome of critically ill patients with and without diabetes mellitus admitted to medical intensive care unit |
| topic | critically ill hyperglycaemia mortality |
| url | http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2022;volume=11;issue=3;spage=157;epage=161;aulast=Lakshmi |
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