Herbal Tea for the Management of Pharyngitis: Inhibition of <i>Streptococcus pyogenes</i> Growth and Biofilm Formation by Herbal Infusions
Herbal teas are becoming popular as functional beverages due to their various health promotional properties. This study aimed at assessing 13 hot water infusions (HWIs) from different herbs against streptococcal pharyngitis (strep throat). Licorice root exhibited the lowest minimum inhibitory concen...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-08-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/7/3/63 |
| _version_ | 1818941074086821888 |
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| author | Niluni M. Wijesundara H. P. Vasantha Rupasinghe |
| author_facet | Niluni M. Wijesundara H. P. Vasantha Rupasinghe |
| author_sort | Niluni M. Wijesundara |
| collection | DOAJ |
| description | Herbal teas are becoming popular as functional beverages due to their various health promotional properties. This study aimed at assessing 13 hot water infusions (HWIs) from different herbs against streptococcal pharyngitis (strep throat). Licorice root exhibited the lowest minimum inhibitory concentrations (MIC) of 1.56 mg/mL, followed by barberry root, thyme, and oregano flowering shoots, with a MIC of 3.13 mg/mL. At their respective minimum bactericidal concentrations (MBC), licorice showed the bactericidal effect on <i>S. pyogenes</i> within 12 h after exposure while others need 24 h for a similar outcome. The HWIs exhibited inhibitory activity on biofilm formation, ranging from 1.56 to 6.25 mg/mL, which confirmed by ruptured cells or clusters of dead cell debris observed in scanning electron microscope (SEM). Overall, non-toxic concentrations of efficacious HWIs from licorice root, barberry root, thyme, and oregano flowering shoots may provide potential sources for developing herbal teas or biomedicine for the management of <i>S. pyogenes</i> infections. |
| first_indexed | 2024-12-20T06:49:45Z |
| format | Article |
| id | doaj.art-b3ed532565e644dca2fe8a05bc3c565a |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-12-20T06:49:45Z |
| publishDate | 2019-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-b3ed532565e644dca2fe8a05bc3c565a2022-12-21T19:49:35ZengMDPI AGBiomedicines2227-90592019-08-01736310.3390/biomedicines7030063biomedicines7030063Herbal Tea for the Management of Pharyngitis: Inhibition of <i>Streptococcus pyogenes</i> Growth and Biofilm Formation by Herbal InfusionsNiluni M. Wijesundara0H. P. Vasantha Rupasinghe1Department of Biology, Faculty of Science, Dalhousie University, Halifax, NS 3H 4R2, CanadaDepartment of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, NS B2N 5E3, CanadaHerbal teas are becoming popular as functional beverages due to their various health promotional properties. This study aimed at assessing 13 hot water infusions (HWIs) from different herbs against streptococcal pharyngitis (strep throat). Licorice root exhibited the lowest minimum inhibitory concentrations (MIC) of 1.56 mg/mL, followed by barberry root, thyme, and oregano flowering shoots, with a MIC of 3.13 mg/mL. At their respective minimum bactericidal concentrations (MBC), licorice showed the bactericidal effect on <i>S. pyogenes</i> within 12 h after exposure while others need 24 h for a similar outcome. The HWIs exhibited inhibitory activity on biofilm formation, ranging from 1.56 to 6.25 mg/mL, which confirmed by ruptured cells or clusters of dead cell debris observed in scanning electron microscope (SEM). Overall, non-toxic concentrations of efficacious HWIs from licorice root, barberry root, thyme, and oregano flowering shoots may provide potential sources for developing herbal teas or biomedicine for the management of <i>S. pyogenes</i> infections.https://www.mdpi.com/2227-9059/7/3/63herbal plantshot water infusionsphytochemicalsnatural health product<i>Streptococcus pyogenes</i>mass spectrometry |
| spellingShingle | Niluni M. Wijesundara H. P. Vasantha Rupasinghe Herbal Tea for the Management of Pharyngitis: Inhibition of <i>Streptococcus pyogenes</i> Growth and Biofilm Formation by Herbal Infusions Biomedicines herbal plants hot water infusions phytochemicals natural health product <i>Streptococcus pyogenes</i> mass spectrometry |
| title | Herbal Tea for the Management of Pharyngitis: Inhibition of <i>Streptococcus pyogenes</i> Growth and Biofilm Formation by Herbal Infusions |
| title_full | Herbal Tea for the Management of Pharyngitis: Inhibition of <i>Streptococcus pyogenes</i> Growth and Biofilm Formation by Herbal Infusions |
| title_fullStr | Herbal Tea for the Management of Pharyngitis: Inhibition of <i>Streptococcus pyogenes</i> Growth and Biofilm Formation by Herbal Infusions |
| title_full_unstemmed | Herbal Tea for the Management of Pharyngitis: Inhibition of <i>Streptococcus pyogenes</i> Growth and Biofilm Formation by Herbal Infusions |
| title_short | Herbal Tea for the Management of Pharyngitis: Inhibition of <i>Streptococcus pyogenes</i> Growth and Biofilm Formation by Herbal Infusions |
| title_sort | herbal tea for the management of pharyngitis inhibition of i streptococcus pyogenes i growth and biofilm formation by herbal infusions |
| topic | herbal plants hot water infusions phytochemicals natural health product <i>Streptococcus pyogenes</i> mass spectrometry |
| url | https://www.mdpi.com/2227-9059/7/3/63 |
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