Synthesis and Antibacterial Evaluation of a New Series of <em>N</em>-Alkyl-2-alkynyl/(<em>E</em>)-alkenyl-4-(1<em>H</em>)-quinolones

Synthesis and Antibacterial Evaluation of a New Series of <em>N</em>-Alkyl-2-alkynyl/(<em>E</em>)-alkenyl-4-(1<em>H</em>)-quinolones

To gain further insight into the structural requirements of the aliphatic group at position 2 for their antimycobacterial activity, some <em>N</em>-alkyl-4-(1<em>H</em>)-quinolones bearing position 2 alkynyls with various chain length and tripl...

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Bibliographic Details
Main Authors: Abraham Wube, Juan-David Guzman, Antje Hüfner, Christina Hochfellner, Martina Blunder, Rudolf Bauer, Simon Gibbons, Sanjib Bhakta, Franz Bucar
Format: Article
Language:English
Published: MDPI AG 2012-07-01
Series:Molecules
Subjects:
<em>N</em>-alkyl-2-alkynyl/(<em>E</em>)-alkenyl-4(1<em>H</em>)-quinolone
antimycobacterial
MRSA
cytotoxicity
Online Access:http://www.mdpi.com/1420-3049/17/7/8217

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