Structural Stabilities and Transformation Mechanism of Rhynchophylline and Isorhynchophylline by Ultra Performance Liquid Chromatography/Time-of-Flight Mass Spectrometry (UPLC/Q-TOF-MS)

Structural Stabilities and Transformation Mechanism of Rhynchophylline and Isorhynchophylline by Ultra Performance Liquid Chromatography/Time-of-Flight Mass Spectrometry (UPLC/Q-TOF-MS)

To reveal the structural stabilities and transformation mechanism of rhynchophylline (RIN) and isorhynchophylline (IRN), HPLC and UPLC-Q-TOF-MS method were developed for the qualitative and quantitative analysis of the conversion rate. The method was validated for linearity, inter- and intra-day pre...

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Bibliographic Details
Main Authors: Zhen-Feng Wu, Ya-Qi Wang, Na Wan, Gang Ke, Peng-Fei Yue, Hao Chen, Juan-Juan Zhan, Ming Yang
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Molecules
Subjects:
rhynchophylline
isorhynchophylline
conversion rate
stability
UPLC-Q-TOF-MS
Online Access:http://www.mdpi.com/1420-3049/20/8/14849

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