Insight into the mechanisms of therapeutic hypothermia for asphyxia cardiac arrest using a comprehensive approach of GC-MS/MS and UPLC-Q-TOF-MS/MS based on serum metabolomics

Insight into the mechanisms of therapeutic hypothermia for asphyxia cardiac arrest using a comprehensive approach of GC-MS/MS and UPLC-Q-TOF-MS/MS based on serum metabolomics

Cardiac arrest (CA) is a severe worldwide health problem. Therapeutic hypothermia is widely used to reduce the cardiac injury and improve the neurological outcomes after CA. However, a few studies have reported the changes of serum metabolic characteristics after CA. The healthy male New Zealand Rab...

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Bibliographic Details
Main Authors: Yiyuan Zhang, Yang Feng, Fang Chen, Jiang Yu, Xiehong Liu, Yanjuan Liu, Jielin Ouyang, Mingyu Liang, Yiming Zhu, Lianhong Zou
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Heliyon
Subjects:
Cardiac arrest
Metabolomics
UPLC-Q-TOF-MS/MS
GC-MS/MS
Hypothermia
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023034540

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