Association between cholangiocarcinoma and liver flukes: review of epidemiological studies
According to official medical statistics, liver fluke infections caused by Opisthorchis felineus, Opisthorchis viverrini and Clonorchis sinensis, are reported annually in the Southeast Asia, European countries and the Russian Federation. These infections are the main cause of digestive system diseas...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2020-04-01
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| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/2695 |
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| author | A. E. Kovshirina O. S. Fedorova Y. V. Kovshirina S. V. Onishchenko S. S. Taslicki L. L. Katanakhova A. V. Chizhikov I. A. Tataurov L. M. Ororodova |
| author_facet | A. E. Kovshirina O. S. Fedorova Y. V. Kovshirina S. V. Onishchenko S. S. Taslicki L. L. Katanakhova A. V. Chizhikov I. A. Tataurov L. M. Ororodova |
| author_sort | A. E. Kovshirina |
| collection | DOAJ |
| description | According to official medical statistics, liver fluke infections caused by Opisthorchis felineus, Opisthorchis viverrini and Clonorchis sinensis, are reported annually in the Southeast Asia, European countries and the Russian Federation. These infections are the main cause of digestive system diseases in the population of endemic regions. The aim of the review is to analyze the findings of epidemiological studies and to assess the relationship between liver and bile duct cancer and Opisthorchiidae liver fluke infections.Materials and methods. The authors reviewed original studies published in 1974–2019 via the MEDLINE databases and the eLIBRARY scientific digital library.Results. The studies have shown that cholangiocarcinoma is a significant medical and social problem in the trematode-endemic areas of Southeast Asia due to the absence of specific symptoms, long asymptomatic course, resistance to therapy and high mortality of patients. Long-term infection caused by trematodes Opisthorchis viverrini and Clonorchis sinensis is associated with a significant risk of developing cholangiocellular cancer. An epidemiological multicenter study is required to establish the relationship between the Opisthorchis felineus infection and cholangiocarcinoma in the population of endemic regions in the Russian Federation. |
| first_indexed | 2024-04-10T01:06:43Z |
| format | Article |
| id | doaj.art-b3f56c58b95948f6a421ebf4538fc5bc |
| institution | Directory Open Access Journal |
| issn | 1682-0363 1819-3684 |
| language | English |
| last_indexed | 2024-04-10T01:06:43Z |
| publishDate | 2020-04-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj.art-b3f56c58b95948f6a421ebf4538fc5bc2023-03-13T09:58:25ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842020-04-0119115015910.20538/1682-0363-2020-1-150-1591608Association between cholangiocarcinoma and liver flukes: review of epidemiological studiesA. E. Kovshirina0O. S. Fedorova1Y. V. Kovshirina2S. V. Onishchenko3S. S. Taslicki4L. L. Katanakhova5A. V. Chizhikov6I. A. Tataurov7L. M. Ororodova8Сибирский государственный медицинский университет (СибГМУ)Сибирский государственный медицинский университет (СибГМУ)Сибирский государственный медицинский университет (СибГМУ)Сургутский государственный университет (СурГУ)Сургутская окружная клиническая больницаСургутский государственный университет (СурГУ)Ханты-Мансийская государственная медицинская академияОкружная клиническая больницаСибирский государственный медицинский университет (СибГМУ)According to official medical statistics, liver fluke infections caused by Opisthorchis felineus, Opisthorchis viverrini and Clonorchis sinensis, are reported annually in the Southeast Asia, European countries and the Russian Federation. These infections are the main cause of digestive system diseases in the population of endemic regions. The aim of the review is to analyze the findings of epidemiological studies and to assess the relationship between liver and bile duct cancer and Opisthorchiidae liver fluke infections.Materials and methods. The authors reviewed original studies published in 1974–2019 via the MEDLINE databases and the eLIBRARY scientific digital library.Results. The studies have shown that cholangiocarcinoma is a significant medical and social problem in the trematode-endemic areas of Southeast Asia due to the absence of specific symptoms, long asymptomatic course, resistance to therapy and high mortality of patients. Long-term infection caused by trematodes Opisthorchis viverrini and Clonorchis sinensis is associated with a significant risk of developing cholangiocellular cancer. An epidemiological multicenter study is required to establish the relationship between the Opisthorchis felineus infection and cholangiocarcinoma in the population of endemic regions in the Russian Federation.https://bulletin.ssmu.ru/jour/article/view/2695opisthorchis viverriniclonorchis sinensisopisthorchis felineusрак печениобзорэпидемиологическое исследование |
| spellingShingle | A. E. Kovshirina O. S. Fedorova Y. V. Kovshirina S. V. Onishchenko S. S. Taslicki L. L. Katanakhova A. V. Chizhikov I. A. Tataurov L. M. Ororodova Association between cholangiocarcinoma and liver flukes: review of epidemiological studies Бюллетень сибирской медицины opisthorchis viverrini clonorchis sinensis opisthorchis felineus рак печени обзор эпидемиологическое исследование |
| title | Association between cholangiocarcinoma and liver flukes: review of epidemiological studies |
| title_full | Association between cholangiocarcinoma and liver flukes: review of epidemiological studies |
| title_fullStr | Association between cholangiocarcinoma and liver flukes: review of epidemiological studies |
| title_full_unstemmed | Association between cholangiocarcinoma and liver flukes: review of epidemiological studies |
| title_short | Association between cholangiocarcinoma and liver flukes: review of epidemiological studies |
| title_sort | association between cholangiocarcinoma and liver flukes review of epidemiological studies |
| topic | opisthorchis viverrini clonorchis sinensis opisthorchis felineus рак печени обзор эпидемиологическое исследование |
| url | https://bulletin.ssmu.ru/jour/article/view/2695 |
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