Expression profiles of NOD-like receptors and regulation of NLRP3 inflammasome activation in Toxoplasma gondii-infected human small intestinal epithelial cells

Expression profiles of NOD-like receptors and regulation of NLRP3 inflammasome activation in Toxoplasma gondii-infected human small intestinal epithelial cells

Abstract Background Toxoplasma gondii is a parasite that primarily infects through the oral route. Nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) play crucial roles in the immune responses generated during parasitic infection and also drive the inflammatory response against in...

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Bibliographic Details
Main Authors: Jia-Qi Chu, Fei Fei Gao, Weiyun Wu, Chunchao Li, Zhaobin Pan, Jinhui Sun, Hao Wang, Cong Huang, Sang Hyuk Lee, Juan-Hua Quan, Young-Ha Lee
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Parasites & Vectors
Subjects:
Toxoplasma gondii
Human small intestinal epithelial cells
NOD-like receptors
Inflammasome
Caspase-cleaved interleukins
Online Access:https://doi.org/10.1186/s13071-021-04666-w

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