Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies

In this article, Sodium alginate and Lignosulphonic acid blends were prepared in different weight ratios by solution casting method. Swelling experiments were conducted for Sodium alginate and its blends by adding calcium chloride for various intervals in a pH 7.4 medium. The strength of the films i...

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Main Authors: S. Giridhar Reddy, Akanksha Saxena Pandit
Format: Article
Language:English
Published: Associação Brasileira de Polímeros 2013-01-01
Series:Polímeros
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282013000100005
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author S. Giridhar Reddy
Akanksha Saxena Pandit
author_facet S. Giridhar Reddy
Akanksha Saxena Pandit
author_sort S. Giridhar Reddy
collection DOAJ
description In this article, Sodium alginate and Lignosulphonic acid blends were prepared in different weight ratios by solution casting method. Swelling experiments were conducted for Sodium alginate and its blends by adding calcium chloride for various intervals in a pH 7.4 medium. The strength of the films increases after their treatment with CaCl2 at higher intervals forming an alginate network. The SA/LS blend (80/20) is subjected for sorption studies at variable pH 1.2 & 7.4, in order to test the suitability of the blends for controlled drug delivery. Further, experiments were conducted for de-crosslinking using 0.1M HCl. The solvent uptake for the blends decreased with increasing LS content in the blends. Blends were investigated by X-ray diffraction and Fourier Transform Infra-Red spectroscopy in order to study the crystallinity and molecular interactions. XRD confirms the reduction in cluster space in blends leading to lower uptake of solvent.
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spelling doaj.art-b3f9ede07e034eceacdc8eb401c87bf32022-12-22T03:56:21ZengAssociação Brasileira de PolímerosPolímeros0104-14281678-51692013-01-012311318Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studiesS. Giridhar ReddyAkanksha Saxena PanditIn this article, Sodium alginate and Lignosulphonic acid blends were prepared in different weight ratios by solution casting method. Swelling experiments were conducted for Sodium alginate and its blends by adding calcium chloride for various intervals in a pH 7.4 medium. The strength of the films increases after their treatment with CaCl2 at higher intervals forming an alginate network. The SA/LS blend (80/20) is subjected for sorption studies at variable pH 1.2 & 7.4, in order to test the suitability of the blends for controlled drug delivery. Further, experiments were conducted for de-crosslinking using 0.1M HCl. The solvent uptake for the blends decreased with increasing LS content in the blends. Blends were investigated by X-ray diffraction and Fourier Transform Infra-Red spectroscopy in order to study the crystallinity and molecular interactions. XRD confirms the reduction in cluster space in blends leading to lower uptake of solvent.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282013000100005Sodium alginateblendsswellingbiomaterialswater soluble polymerscrosslinking
spellingShingle S. Giridhar Reddy
Akanksha Saxena Pandit
Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
Polímeros
Sodium alginate
blends
swelling
biomaterials
water soluble polymers
crosslinking
title Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
title_full Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
title_fullStr Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
title_full_unstemmed Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
title_short Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
title_sort biodegradable sodium alginate and lignosulphonic acid blends characterization and swelling studies
topic Sodium alginate
blends
swelling
biomaterials
water soluble polymers
crosslinking
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282013000100005
work_keys_str_mv AT sgiridharreddy biodegradablesodiumalginateandlignosulphonicacidblendscharacterizationandswellingstudies
AT akankshasaxenapandit biodegradablesodiumalginateandlignosulphonicacidblendscharacterizationandswellingstudies