Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies
In this article, Sodium alginate and Lignosulphonic acid blends were prepared in different weight ratios by solution casting method. Swelling experiments were conducted for Sodium alginate and its blends by adding calcium chloride for various intervals in a pH 7.4 medium. The strength of the films i...
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Format: | Article |
Language: | English |
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Associação Brasileira de Polímeros
2013-01-01
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Series: | Polímeros |
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Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282013000100005 |
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author | S. Giridhar Reddy Akanksha Saxena Pandit |
author_facet | S. Giridhar Reddy Akanksha Saxena Pandit |
author_sort | S. Giridhar Reddy |
collection | DOAJ |
description | In this article, Sodium alginate and Lignosulphonic acid blends were prepared in different weight ratios by solution casting method. Swelling experiments were conducted for Sodium alginate and its blends by adding calcium chloride for various intervals in a pH 7.4 medium. The strength of the films increases after their treatment with CaCl2 at higher intervals forming an alginate network. The SA/LS blend (80/20) is subjected for sorption studies at variable pH 1.2 & 7.4, in order to test the suitability of the blends for controlled drug delivery. Further, experiments were conducted for de-crosslinking using 0.1M HCl. The solvent uptake for the blends decreased with increasing LS content in the blends. Blends were investigated by X-ray diffraction and Fourier Transform Infra-Red spectroscopy in order to study the crystallinity and molecular interactions. XRD confirms the reduction in cluster space in blends leading to lower uptake of solvent. |
first_indexed | 2024-04-11T23:56:39Z |
format | Article |
id | doaj.art-b3f9ede07e034eceacdc8eb401c87bf3 |
institution | Directory Open Access Journal |
issn | 0104-1428 1678-5169 |
language | English |
last_indexed | 2024-04-11T23:56:39Z |
publishDate | 2013-01-01 |
publisher | Associação Brasileira de Polímeros |
record_format | Article |
series | Polímeros |
spelling | doaj.art-b3f9ede07e034eceacdc8eb401c87bf32022-12-22T03:56:21ZengAssociação Brasileira de PolímerosPolímeros0104-14281678-51692013-01-012311318Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studiesS. Giridhar ReddyAkanksha Saxena PanditIn this article, Sodium alginate and Lignosulphonic acid blends were prepared in different weight ratios by solution casting method. Swelling experiments were conducted for Sodium alginate and its blends by adding calcium chloride for various intervals in a pH 7.4 medium. The strength of the films increases after their treatment with CaCl2 at higher intervals forming an alginate network. The SA/LS blend (80/20) is subjected for sorption studies at variable pH 1.2 & 7.4, in order to test the suitability of the blends for controlled drug delivery. Further, experiments were conducted for de-crosslinking using 0.1M HCl. The solvent uptake for the blends decreased with increasing LS content in the blends. Blends were investigated by X-ray diffraction and Fourier Transform Infra-Red spectroscopy in order to study the crystallinity and molecular interactions. XRD confirms the reduction in cluster space in blends leading to lower uptake of solvent.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282013000100005Sodium alginateblendsswellingbiomaterialswater soluble polymerscrosslinking |
spellingShingle | S. Giridhar Reddy Akanksha Saxena Pandit Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies Polímeros Sodium alginate blends swelling biomaterials water soluble polymers crosslinking |
title | Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies |
title_full | Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies |
title_fullStr | Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies |
title_full_unstemmed | Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies |
title_short | Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies |
title_sort | biodegradable sodium alginate and lignosulphonic acid blends characterization and swelling studies |
topic | Sodium alginate blends swelling biomaterials water soluble polymers crosslinking |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282013000100005 |
work_keys_str_mv | AT sgiridharreddy biodegradablesodiumalginateandlignosulphonicacidblendscharacterizationandswellingstudies AT akankshasaxenapandit biodegradablesodiumalginateandlignosulphonicacidblendscharacterizationandswellingstudies |