Sox15 Methylation Inhibits Cell Proliferation Through Wnt Signaling in Hepatocellular Carcinoma

Sox15 Methylation Inhibits Cell Proliferation Through Wnt Signaling in Hepatocellular Carcinoma

The expression of the SRY-Box Transcription Factor 15 (Sox15) is reduced by DNA methylation, and its progression is suppressed within numerous tumors. However, its effect on hepatocellular carcinoma (HCC) remains unknown. In the present work, the clinical importance and function of Sox15, as well as...

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Bibliographic Details
Main Authors: Bajin Wei, Hao Chen, Xiaobin Chen, Danjing Guo, Liangjie Hong, Shusen Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Oncology
Subjects:
SOX15
HCC
Wnt signaling
cell proliferation
methylation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.842312/full

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