Lipid metabolism in tumor immunology and immunotherapy
Lipids are a diverse class of biomolecules that have been implicated in cancer pathophysiology and in an array of immune responses, making them potential targets for improving immune responsiveness. Lipid and lipid oxidation also can affect tumor progression and response to treatment. Although their...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1187279/full |
| _version_ | 1797368339205455872 |
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| author | Lisa K. Duong Halil Ibrahim Corbali Halil Ibrahim Corbali Thomas S. Riad Shonik Ganjoo Selene Nanez Tiffany Voss Hampartsoum B. Barsoumian James Welsh Maria Angelica Cortez |
| author_facet | Lisa K. Duong Halil Ibrahim Corbali Halil Ibrahim Corbali Thomas S. Riad Shonik Ganjoo Selene Nanez Tiffany Voss Hampartsoum B. Barsoumian James Welsh Maria Angelica Cortez |
| author_sort | Lisa K. Duong |
| collection | DOAJ |
| description | Lipids are a diverse class of biomolecules that have been implicated in cancer pathophysiology and in an array of immune responses, making them potential targets for improving immune responsiveness. Lipid and lipid oxidation also can affect tumor progression and response to treatment. Although their importance in cellular functions and their potential as cancer biomarkers have been explored, lipids have yet to be extensively investigated as a possible form of cancer therapy. This review explores the role of lipids in cancer pathophysiology and describes how further understanding of these macromolecules could prompt novel treatments for cancer. |
| first_indexed | 2024-03-08T17:30:58Z |
| format | Article |
| id | doaj.art-b3ffb97e286a4aaeaec6813677aad840 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-03-08T17:30:58Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-b3ffb97e286a4aaeaec6813677aad8402024-01-02T15:25:07ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-05-011310.3389/fonc.2023.11872791187279Lipid metabolism in tumor immunology and immunotherapyLisa K. Duong0Halil Ibrahim Corbali1Halil Ibrahim Corbali2Thomas S. Riad3Shonik Ganjoo4Selene Nanez5Tiffany Voss6Hampartsoum B. Barsoumian7James Welsh8Maria Angelica Cortez9Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United StatesDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United StatesDepartment of Medical Pharmacology, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, TürkiyeDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United StatesDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United StatesDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United StatesDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United StatesDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United StatesDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United StatesDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United StatesLipids are a diverse class of biomolecules that have been implicated in cancer pathophysiology and in an array of immune responses, making them potential targets for improving immune responsiveness. Lipid and lipid oxidation also can affect tumor progression and response to treatment. Although their importance in cellular functions and their potential as cancer biomarkers have been explored, lipids have yet to be extensively investigated as a possible form of cancer therapy. This review explores the role of lipids in cancer pathophysiology and describes how further understanding of these macromolecules could prompt novel treatments for cancer.https://www.frontiersin.org/articles/10.3389/fonc.2023.1187279/fulllipidslipid oxidationimmunotherapycancerimmune cells |
| spellingShingle | Lisa K. Duong Halil Ibrahim Corbali Halil Ibrahim Corbali Thomas S. Riad Shonik Ganjoo Selene Nanez Tiffany Voss Hampartsoum B. Barsoumian James Welsh Maria Angelica Cortez Lipid metabolism in tumor immunology and immunotherapy Frontiers in Oncology lipids lipid oxidation immunotherapy cancer immune cells |
| title | Lipid metabolism in tumor immunology and immunotherapy |
| title_full | Lipid metabolism in tumor immunology and immunotherapy |
| title_fullStr | Lipid metabolism in tumor immunology and immunotherapy |
| title_full_unstemmed | Lipid metabolism in tumor immunology and immunotherapy |
| title_short | Lipid metabolism in tumor immunology and immunotherapy |
| title_sort | lipid metabolism in tumor immunology and immunotherapy |
| topic | lipids lipid oxidation immunotherapy cancer immune cells |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1187279/full |
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