Risk Factors for Severe Postoperative Complications after Oncologic Right Colectomy: Unicenter Analysis
<i>Background and Objectives:</i> This study aimed to investigate the potential risk factors for severe postoperative complications after oncologic right colectomy. <i>Materials and Methods</i>: All consecutive patients with right colon cancer who underwent right colectomy in...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-11-01
|
| Series: | Medicina |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1648-9144/58/11/1598 |
| _version_ | 1797467336349843456 |
|---|---|
| author | Eugenia Claudia Zarnescu Narcis Octavian Zarnescu Nicoleta Sanda Radu Costea |
| author_facet | Eugenia Claudia Zarnescu Narcis Octavian Zarnescu Nicoleta Sanda Radu Costea |
| author_sort | Eugenia Claudia Zarnescu |
| collection | DOAJ |
| description | <i>Background and Objectives:</i> This study aimed to investigate the potential risk factors for severe postoperative complications after oncologic right colectomy. <i>Materials and Methods</i>: All consecutive patients with right colon cancer who underwent right colectomy in our department between 2016 and 2021 were retrospectively included in this study. The Clavien–Dindo grading system was used to evaluate postoperative complications. Univariate and multivariate logistic regression analyses were used to investigate risk factors for postoperative severe complications. <i>Results</i>: Of the 144 patients, there were 69 males and 75 females, with a median age of 69 (IQR 60–78). Postoperative morbidity and mortality rates were 41.7% (60 patients) and 11.1% (16 patients), respectively. The anastomotic leak rate was 5.3% (7 patients). Severe postoperative complications (Clavien–Dindo grades III–V) were present in 20 patients (13.9%). Univariate analysis showed the following as risk factors for postoperative severe complications: Charlson score, lack of mechanical bowel preparation, level of preoperative proteins, blood transfusions, and degree of urgency (elective/emergency right colectomy). In the logistic binary regression, the Charlson score (OR = 1.931, 95% CI = 1.077–3.463, <i>p</i> = 0.025) and preoperative protein level (OR = 0.049, 95% CI = 0.006–0.433, <i>p</i> = 0.007) were found to be independent risk factors for postoperative severe complications. <i>Conclusions</i>: Severe complications after oncologic right colectomy are associated with a low preoperative protein level and a higher Charlson comorbidity index. |
| first_indexed | 2024-03-09T18:52:10Z |
| format | Article |
| id | doaj.art-b3ffd9c3fcfd4854bdd224809f15e0f5 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T18:52:10Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-b3ffd9c3fcfd4854bdd224809f15e0f52023-11-24T05:47:25ZengMDPI AGMedicina1010-660X1648-91442022-11-015811159810.3390/medicina58111598Risk Factors for Severe Postoperative Complications after Oncologic Right Colectomy: Unicenter AnalysisEugenia Claudia Zarnescu0Narcis Octavian Zarnescu1Nicoleta Sanda2Radu Costea3Department of General Surgery, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of General Surgery, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of General Surgery, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of General Surgery, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania<i>Background and Objectives:</i> This study aimed to investigate the potential risk factors for severe postoperative complications after oncologic right colectomy. <i>Materials and Methods</i>: All consecutive patients with right colon cancer who underwent right colectomy in our department between 2016 and 2021 were retrospectively included in this study. The Clavien–Dindo grading system was used to evaluate postoperative complications. Univariate and multivariate logistic regression analyses were used to investigate risk factors for postoperative severe complications. <i>Results</i>: Of the 144 patients, there were 69 males and 75 females, with a median age of 69 (IQR 60–78). Postoperative morbidity and mortality rates were 41.7% (60 patients) and 11.1% (16 patients), respectively. The anastomotic leak rate was 5.3% (7 patients). Severe postoperative complications (Clavien–Dindo grades III–V) were present in 20 patients (13.9%). Univariate analysis showed the following as risk factors for postoperative severe complications: Charlson score, lack of mechanical bowel preparation, level of preoperative proteins, blood transfusions, and degree of urgency (elective/emergency right colectomy). In the logistic binary regression, the Charlson score (OR = 1.931, 95% CI = 1.077–3.463, <i>p</i> = 0.025) and preoperative protein level (OR = 0.049, 95% CI = 0.006–0.433, <i>p</i> = 0.007) were found to be independent risk factors for postoperative severe complications. <i>Conclusions</i>: Severe complications after oncologic right colectomy are associated with a low preoperative protein level and a higher Charlson comorbidity index.https://www.mdpi.com/1648-9144/58/11/1598Clavien–Dindo classificationrisk factorsright colon cancerright colectomysevere complicationsnutrition |
| spellingShingle | Eugenia Claudia Zarnescu Narcis Octavian Zarnescu Nicoleta Sanda Radu Costea Risk Factors for Severe Postoperative Complications after Oncologic Right Colectomy: Unicenter Analysis Medicina Clavien–Dindo classification risk factors right colon cancer right colectomy severe complications nutrition |
| title | Risk Factors for Severe Postoperative Complications after Oncologic Right Colectomy: Unicenter Analysis |
| title_full | Risk Factors for Severe Postoperative Complications after Oncologic Right Colectomy: Unicenter Analysis |
| title_fullStr | Risk Factors for Severe Postoperative Complications after Oncologic Right Colectomy: Unicenter Analysis |
| title_full_unstemmed | Risk Factors for Severe Postoperative Complications after Oncologic Right Colectomy: Unicenter Analysis |
| title_short | Risk Factors for Severe Postoperative Complications after Oncologic Right Colectomy: Unicenter Analysis |
| title_sort | risk factors for severe postoperative complications after oncologic right colectomy unicenter analysis |
| topic | Clavien–Dindo classification risk factors right colon cancer right colectomy severe complications nutrition |
| url | https://www.mdpi.com/1648-9144/58/11/1598 |
| work_keys_str_mv | AT eugeniaclaudiazarnescu riskfactorsforseverepostoperativecomplicationsafteroncologicrightcolectomyunicenteranalysis AT narcisoctavianzarnescu riskfactorsforseverepostoperativecomplicationsafteroncologicrightcolectomyunicenteranalysis AT nicoletasanda riskfactorsforseverepostoperativecomplicationsafteroncologicrightcolectomyunicenteranalysis AT raducostea riskfactorsforseverepostoperativecomplicationsafteroncologicrightcolectomyunicenteranalysis |