3D-printed mouthpiece adapter for sampling exhaled breath in medical applications

Abstract The growing use of 3D printing in the biomedical sciences demonstrates its utility for a wide range of research and healthcare applications, including its potential implementation in the discipline of breath analysis to overcome current limitations and substantial costs of commercial breath...

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Main Authors: Y Lan Pham, Jonathan Beauchamp, Alexander Clement, Felix Wiegandt, Olaf Holz
Format: Article
Language:English
Published: BMC 2022-08-01
Series:3D Printing in Medicine
Subjects:
Online Access:https://doi.org/10.1186/s41205-022-00150-y
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author Y Lan Pham
Jonathan Beauchamp
Alexander Clement
Felix Wiegandt
Olaf Holz
author_facet Y Lan Pham
Jonathan Beauchamp
Alexander Clement
Felix Wiegandt
Olaf Holz
author_sort Y Lan Pham
collection DOAJ
description Abstract The growing use of 3D printing in the biomedical sciences demonstrates its utility for a wide range of research and healthcare applications, including its potential implementation in the discipline of breath analysis to overcome current limitations and substantial costs of commercial breath sampling interfaces. This technical note reports on the design and construction of a 3D-printed mouthpiece adapter for sampling exhaled breath using the commercial respiration collector for in-vitro analysis (ReCIVA) device. The paper presents the design and digital workflow transition of the adapter and its fabrication from three commercial resins (Surgical Guide, Tough v5, and BioMed Clear) using a Formlabs Form 3B stereolithography (SLA) printer. The use of the mouthpiece adapter in conjunction with a pulmonary function filter is appraised in comparison to the conventional commercial silicon facemask sampling interface. Besides its lower cost – investment cost of the printing equipment notwithstanding – the 3D-printed adapter has several benefits, including ensuring breath sampling via the mouth, reducing the likelihood of direct contact of the patient with the breath sampling tubes, and being autoclaveable to enable the repeated use of a single adapter, thereby reducing waste and associated environmental burden compared to current one-way disposable facemasks. The novel adapter for breath sampling presented in this technical note represents an additional field of application for 3D printing that further demonstrates its widespread applicability in biomedicine.
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spelling doaj.art-b409d1dfb9ac4193adf3e845d44b1d952022-12-22T01:35:40ZengBMC3D Printing in Medicine2365-62712022-08-01811810.1186/s41205-022-00150-y3D-printed mouthpiece adapter for sampling exhaled breath in medical applicationsY Lan Pham0Jonathan Beauchamp1Alexander Clement2Felix Wiegandt3Olaf Holz4Fraunhofer Institute for Process Engineering and Packaging IVVFraunhofer Institute for Process Engineering and Packaging IVVFraunhofer Institute for Toxicology and Experimental Medicine ITEMFraunhofer Institute for Toxicology and Experimental Medicine ITEMFraunhofer Institute for Toxicology and Experimental Medicine ITEMAbstract The growing use of 3D printing in the biomedical sciences demonstrates its utility for a wide range of research and healthcare applications, including its potential implementation in the discipline of breath analysis to overcome current limitations and substantial costs of commercial breath sampling interfaces. This technical note reports on the design and construction of a 3D-printed mouthpiece adapter for sampling exhaled breath using the commercial respiration collector for in-vitro analysis (ReCIVA) device. The paper presents the design and digital workflow transition of the adapter and its fabrication from three commercial resins (Surgical Guide, Tough v5, and BioMed Clear) using a Formlabs Form 3B stereolithography (SLA) printer. The use of the mouthpiece adapter in conjunction with a pulmonary function filter is appraised in comparison to the conventional commercial silicon facemask sampling interface. Besides its lower cost – investment cost of the printing equipment notwithstanding – the 3D-printed adapter has several benefits, including ensuring breath sampling via the mouth, reducing the likelihood of direct contact of the patient with the breath sampling tubes, and being autoclaveable to enable the repeated use of a single adapter, thereby reducing waste and associated environmental burden compared to current one-way disposable facemasks. The novel adapter for breath sampling presented in this technical note represents an additional field of application for 3D printing that further demonstrates its widespread applicability in biomedicine.https://doi.org/10.1186/s41205-022-00150-yPrototypingSampling InterfaceResin-printed DeviceStereolithographyBreath AnalysisSpirometry
spellingShingle Y Lan Pham
Jonathan Beauchamp
Alexander Clement
Felix Wiegandt
Olaf Holz
3D-printed mouthpiece adapter for sampling exhaled breath in medical applications
3D Printing in Medicine
Prototyping
Sampling Interface
Resin-printed Device
Stereolithography
Breath Analysis
Spirometry
title 3D-printed mouthpiece adapter for sampling exhaled breath in medical applications
title_full 3D-printed mouthpiece adapter for sampling exhaled breath in medical applications
title_fullStr 3D-printed mouthpiece adapter for sampling exhaled breath in medical applications
title_full_unstemmed 3D-printed mouthpiece adapter for sampling exhaled breath in medical applications
title_short 3D-printed mouthpiece adapter for sampling exhaled breath in medical applications
title_sort 3d printed mouthpiece adapter for sampling exhaled breath in medical applications
topic Prototyping
Sampling Interface
Resin-printed Device
Stereolithography
Breath Analysis
Spirometry
url https://doi.org/10.1186/s41205-022-00150-y
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