Astragalus polysaccharides protects thapsigargin-induced endoplasmic reticulum stress in HT29 cells
This study investigates the effect of astragalus polysaccharides (APS) in protecting against thapsigargin-induced endoplasmic reticulum (ER) stress in HT29 cells by suppressing the PERK-eIF2a signaling pathway.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2019-12-01
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| Series: | Open Life Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/biol-2019-0055 |
| _version_ | 1819096014607351808 |
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| author | Zheng Lie Zhang Ya-Li Chen Xuan Chen De-Liang Dai Yan-Cheng Tang Zhi-Peng |
| author_facet | Zheng Lie Zhang Ya-Li Chen Xuan Chen De-Liang Dai Yan-Cheng Tang Zhi-Peng |
| author_sort | Zheng Lie |
| collection | DOAJ |
| description | This study investigates the effect of astragalus polysaccharides (APS) in protecting against thapsigargin-induced endoplasmic reticulum (ER) stress in HT29 cells by suppressing the PERK-eIF2a signaling pathway. |
| first_indexed | 2024-12-21T23:52:28Z |
| format | Article |
| id | doaj.art-b410699b7eb54078a3b25faa6985558f |
| institution | Directory Open Access Journal |
| issn | 2391-5412 |
| language | English |
| last_indexed | 2024-12-21T23:52:28Z |
| publishDate | 2019-12-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Life Sciences |
| spelling | doaj.art-b410699b7eb54078a3b25faa6985558f2022-12-21T18:45:54ZengDe GruyterOpen Life Sciences2391-54122019-12-0114149450110.1515/biol-2019-0055biol-2019-0055Astragalus polysaccharides protects thapsigargin-induced endoplasmic reticulum stress in HT29 cellsZheng Lie0Zhang Ya-Li1Chen Xuan2Chen De-Liang3Dai Yan-Cheng4Tang Zhi-Peng5Institute of Digestive Diseases, LongHua Hospital, Shanghai University of Traditional Chinese Medicine, 725 Wanping Road, Shanghai200032, ChinaInstitute of Digestive Diseases, LongHua Hospital, Shanghai University of Traditional Chinese Medicine, 725 Wanping Road, Shanghai200032, ChinaShanghai University of Traditional Chinese Medicine, Shanghai201203, ChinaInstitute of Digestive Diseases, LongHua Hospital, Shanghai University of Traditional Chinese Medicine, 725 Wanping Road, Shanghai200032, ChinaInstitute of Digestive Diseases, LongHua Hospital, Shanghai University of Traditional Chinese Medicine, 725 Wanping Road, Shanghai200032, ChinaInstitute of Digestive Diseases, LongHua Hospital, Shanghai University of Traditional Chinese Medicine, 725 Wanping Road, Shanghai200032, ChinaThis study investigates the effect of astragalus polysaccharides (APS) in protecting against thapsigargin-induced endoplasmic reticulum (ER) stress in HT29 cells by suppressing the PERK-eIF2a signaling pathway.https://doi.org/10.1515/biol-2019-0055astragalus polysaccharidesthapsigarginer stressht29 cellsperk-eif2a signaling |
| spellingShingle | Zheng Lie Zhang Ya-Li Chen Xuan Chen De-Liang Dai Yan-Cheng Tang Zhi-Peng Astragalus polysaccharides protects thapsigargin-induced endoplasmic reticulum stress in HT29 cells Open Life Sciences astragalus polysaccharides thapsigargin er stress ht29 cells perk-eif2a signaling |
| title | Astragalus polysaccharides protects thapsigargin-induced endoplasmic reticulum stress in HT29 cells |
| title_full | Astragalus polysaccharides protects thapsigargin-induced endoplasmic reticulum stress in HT29 cells |
| title_fullStr | Astragalus polysaccharides protects thapsigargin-induced endoplasmic reticulum stress in HT29 cells |
| title_full_unstemmed | Astragalus polysaccharides protects thapsigargin-induced endoplasmic reticulum stress in HT29 cells |
| title_short | Astragalus polysaccharides protects thapsigargin-induced endoplasmic reticulum stress in HT29 cells |
| title_sort | astragalus polysaccharides protects thapsigargin induced endoplasmic reticulum stress in ht29 cells |
| topic | astragalus polysaccharides thapsigargin er stress ht29 cells perk-eif2a signaling |
| url | https://doi.org/10.1515/biol-2019-0055 |
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