Genome-wide SNP analysis of Plasmodium falciparum shows differentiation at drug-resistance-associated loci among malaria transmission settings in southern Mali

Genome-wide SNP analysis of Plasmodium falciparum shows differentiation at drug-resistance-associated loci among malaria transmission settings in southern Mali

Plasmodium falciparum malaria cases in Africa represent over 90% of the global burden with Mali being amongst the 11 highest burden countries that account for 70% of this annual incidence. The persistence of P. falciparum despite massive global interventions is because of its genetic diversity that...

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Bibliographic Details
Main Authors: Aoua Coulibaly, Mouhamadou Fadel Diop, Aminatou Kone, Antoine Dara, Amed Ouattara, Nicola Mulder, Olivo Miotto, Mahamadou Diakite, Abdoulaye Djimde, Alfred Amambua-Ngwa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Genetics
Subjects:
malaria
drug resistance
genetic variation
positive selection
differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.943445/full

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