Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans
Abstract Background Some previous works have focused on dose‐response relationship between cocoa consumption and blood pressure in Caucasians. As black subjects have lower nitric oxide bioavailability, the aim of this work was to determine the dose‐effect relation between cocoa and blood pressure in...
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| Format: | Article |
| Language: | English |
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Wiley
2021-10-01
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| Series: | Physiological Reports |
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| Online Access: | https://doi.org/10.14814/phy2.15070 |
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| author | Edwige Balayssac‐Siransy Soualiho Ouattara Kotchi Joël Michée Boka Hugues Ahiboh Téniloh Augustin Yéo Paule‐Denise Yapo Aya Liliane Kondo Walamitien Cyrille Touré Kotchi Fabrice Edé Cyrille Serges Dah Pascal Bogui |
| author_facet | Edwige Balayssac‐Siransy Soualiho Ouattara Kotchi Joël Michée Boka Hugues Ahiboh Téniloh Augustin Yéo Paule‐Denise Yapo Aya Liliane Kondo Walamitien Cyrille Touré Kotchi Fabrice Edé Cyrille Serges Dah Pascal Bogui |
| author_sort | Edwige Balayssac‐Siransy |
| collection | DOAJ |
| description | Abstract Background Some previous works have focused on dose‐response relationship between cocoa consumption and blood pressure in Caucasians. As black subjects have lower nitric oxide bioavailability, the aim of this work was to determine the dose‐effect relation between cocoa and blood pressure in black Africans. Method One hundred and thirty healthy black African males aged 18–30 were randomly assigned into four groups: three groups consuming 10 g, 5 g, or 2 g of cocoa powder daily for three weeks and one control group that did not consume cocoa. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured on day 1 (D1, before any subject consumed cocoa), D8, D15, and D22. Means of the parameters at each of the four visits and changes of the means were compared among the groups. Results Significant decrease in SBP was noted in consumers of 10 g compared to controls in the 1st week, and compared to consumers of 2 g in the 2nd and 3rd weeks of follow‐up. Means and changes of DBP were statistically similar among the four groups. Conclusion Among our cohort, decrease in SBP was significantly greater in the heavy cocoa consumer group (10 g) compared to the low consumer group (2 g), but there was no statistically significant difference when compared with the intermediate consumer group (5 g). The dose‐response relationship between cocoa consumption and changes in SBP was not linear. No relationship was found between cocoa consumption and DBP. |
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| issn | 2051-817X |
| language | English |
| last_indexed | 2024-12-18T00:36:44Z |
| publishDate | 2021-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | Physiological Reports |
| spelling | doaj.art-b411d44f0dca48c286f5e031f1c5a3d02022-12-21T21:27:00ZengWileyPhysiological Reports2051-817X2021-10-01920n/an/a10.14814/phy2.15070Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black AfricansEdwige Balayssac‐Siransy0Soualiho Ouattara1Kotchi Joël Michée Boka2Hugues Ahiboh3Téniloh Augustin Yéo4Paule‐Denise Yapo5Aya Liliane Kondo6Walamitien Cyrille Touré7Kotchi Fabrice Edé8Cyrille Serges Dah9Pascal Bogui10Laboratoire de Physiologie et d’Explorations Fonctionnelles Unité de Formation et de Recherche en Sciences Médicales Université Félix Houphouët‐Boigny Abidjan Côte d’IvoireLaboratoire de Physiologie et d’Explorations Fonctionnelles Unité de Formation et de Recherche en Sciences Médicales Université Félix Houphouët‐Boigny Abidjan Côte d’IvoireLaboratoire de Physiologie et d’Explorations Fonctionnelles Unité de Formation et de Recherche en Sciences Médicales Université Félix Houphouët‐Boigny Abidjan Côte d’IvoireLaboratoire de Biochimie Unité de Formation et de Recherche en Sciences Pharmaceutiques et Biologiques Université Félix Houphouët‐Boigny Abidjan Côte d’IvoireLaboratoire de Physiologie et d’Explorations Fonctionnelles Unité de Formation et de Recherche en Sciences Médicales Université Félix Houphouët‐Boigny Abidjan Côte d’IvoireLaboratoire de Physiologie et d’Explorations Fonctionnelles Unité de Formation et de Recherche en Sciences Médicales Université Félix Houphouët‐Boigny Abidjan Côte d’IvoireLaboratoire de Physiologie et d’Explorations Fonctionnelles Unité de Formation et de Recherche en Sciences Médicales Université Félix Houphouët‐Boigny Abidjan Côte d’IvoireLaboratoire de Physiologie et d’Explorations Fonctionnelles Unité de Formation et de Recherche en Sciences Médicales Université Félix Houphouët‐Boigny Abidjan Côte d’IvoireLaboratoire de Physiologie et d’Explorations Fonctionnelles Unité de Formation et de Recherche en Sciences Médicales Université Félix Houphouët‐Boigny Abidjan Côte d’IvoireLaboratoire de Physiologie et d’Explorations Fonctionnelles Unité de Formation et de Recherche en Sciences Médicales Université Félix Houphouët‐Boigny Abidjan Côte d’IvoireLaboratoire de Physiologie et d’Explorations Fonctionnelles Unité de Formation et de Recherche en Sciences Médicales Université Félix Houphouët‐Boigny Abidjan Côte d’IvoireAbstract Background Some previous works have focused on dose‐response relationship between cocoa consumption and blood pressure in Caucasians. As black subjects have lower nitric oxide bioavailability, the aim of this work was to determine the dose‐effect relation between cocoa and blood pressure in black Africans. Method One hundred and thirty healthy black African males aged 18–30 were randomly assigned into four groups: three groups consuming 10 g, 5 g, or 2 g of cocoa powder daily for three weeks and one control group that did not consume cocoa. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured on day 1 (D1, before any subject consumed cocoa), D8, D15, and D22. Means of the parameters at each of the four visits and changes of the means were compared among the groups. Results Significant decrease in SBP was noted in consumers of 10 g compared to controls in the 1st week, and compared to consumers of 2 g in the 2nd and 3rd weeks of follow‐up. Means and changes of DBP were statistically similar among the four groups. Conclusion Among our cohort, decrease in SBP was significantly greater in the heavy cocoa consumer group (10 g) compared to the low consumer group (2 g), but there was no statistically significant difference when compared with the intermediate consumer group (5 g). The dose‐response relationship between cocoa consumption and changes in SBP was not linear. No relationship was found between cocoa consumption and DBP.https://doi.org/10.14814/phy2.15070black Africanblood pressurecocoadose‐effect |
| spellingShingle | Edwige Balayssac‐Siransy Soualiho Ouattara Kotchi Joël Michée Boka Hugues Ahiboh Téniloh Augustin Yéo Paule‐Denise Yapo Aya Liliane Kondo Walamitien Cyrille Touré Kotchi Fabrice Edé Cyrille Serges Dah Pascal Bogui Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans Physiological Reports black African blood pressure cocoa dose‐effect |
| title | Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans |
| title_full | Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans |
| title_fullStr | Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans |
| title_full_unstemmed | Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans |
| title_short | Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans |
| title_sort | dose effect relation between regular consumption of 100 cocoa powder and blood pressure in young healthy black africans |
| topic | black African blood pressure cocoa dose‐effect |
| url | https://doi.org/10.14814/phy2.15070 |
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