Network pharmacology, computational biology integrated surface plasmon resonance technology reveals the mechanism of ellagic acid against rotavirus

Network pharmacology, computational biology integrated surface plasmon resonance technology reveals the mechanism of ellagic acid against rotavirus

Abstract The target and mechanism of ellagic acid (EA) against rotavirus (RV) were investigated by network pharmacology, computational biology, and surface plasmon resonance verification. The target of EA was obtained from 11 databases such as HIT and TCMSP, and RV-related targets were obtained from...

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Bibliographic Details
Main Authors:	Jiangang Zheng, Abdul Haseeb, Ziyang Wang, Hejie Wang
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-03-01
Series:	Scientific Reports
Subjects:	Ellagic acid Rotavirus Network pharmacology Molecular docking Molecular dynamics simulation Saturation mutation analysis
Online Access:	https://doi.org/10.1038/s41598-024-58301-6

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