Application of chitosan-based wound coatings ‘ChitoPran’ in the treatment of patients with burn trauma
Introduction. The analysis of clinical experience for using biodegradable wound coating based on «HitoPran» chitosan in treatment of patients with burn trauma is presented.Background. Our work included an analysis of clinical experience for using a biodegradable wound coating based on «HitoPran» chi...
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| Format: | Article |
| Language: | Russian |
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Scientific Research Institute, Ochapovsky Regional Clinical Hospital no. 1
2019-09-01
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| Series: | Инновационная медицина Кубани |
| Subjects: | |
| Online Access: | https://www.innovmedkub.ru/jour/article/view/207 |
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| author | A. V. Polyakov S. B. Bogdanov I. M. Afanasov A. V. Karakulev Y. A. Bogdanova E. V. Zinoviev K. F. Osmanov |
| author_facet | A. V. Polyakov S. B. Bogdanov I. M. Afanasov A. V. Karakulev Y. A. Bogdanova E. V. Zinoviev K. F. Osmanov |
| author_sort | A. V. Polyakov |
| collection | DOAJ |
| description | Introduction. The analysis of clinical experience for using biodegradable wound coating based on «HitoPran» chitosan in treatment of patients with burn trauma is presented.Background. Our work included an analysis of clinical experience for using a biodegradable wound coating based on «HitoPran» chitosan for surgical treatment in patients with local and common thermal burns.Material and Methods. A treatment analysis was conducted in 46 male and female patients, aged from 1 to 63 years with thermal burns on an area of 5 to 56% of the body surface. All injured were given surgical treatment in the complex with the use of low-temperature air plasma of arc discharge with atmospheric pressure in the conditions of our burn center in 2017–2018. Depending on the area and depth of the lesion, the patients were divided into two clinical groups: with local burns of II degree and area to 5% of the body surface and common burns of II and III degree and body surface 10% and more. In the course of early surgical treatment in patients with local border burns, the use of the wound coating «HitoPran» allows to achieve spontaneous epithelialization of wounds in dry environment after dermabrasion or escharotomy within the surface layers of dermis due to chitosan adhesion to the wound bottom, to reduce the number of dressings in the postoperative period. Covering skin grafts with perforation index 1:4 and 1:6 with wound «ChitoPran» coating in case of autodermoplasty in deep burn wounds provides satisfactory cellular epithelialization, reduces risk of regression of grafts, reduces consumption of wound coating and dressing material.Conclusion. Application of Russian modern biodegradable coatings based on «HitoPran» chitosan in complex treatment in patients with local and common burns with different depth allows to optimize local treatment of burn injuries, as well as to reduce the cost of used dressing material in comparison with foreign alternatives. |
| first_indexed | 2024-03-07T15:35:59Z |
| format | Article |
| id | doaj.art-b415780a53c84fbcb1b82973b36dd324 |
| institution | Directory Open Access Journal |
| issn | 2541-9897 |
| language | Russian |
| last_indexed | 2024-03-07T15:35:59Z |
| publishDate | 2019-09-01 |
| publisher | Scientific Research Institute, Ochapovsky Regional Clinical Hospital no. 1 |
| record_format | Article |
| series | Инновационная медицина Кубани |
| spelling | doaj.art-b415780a53c84fbcb1b82973b36dd3242024-03-05T11:12:30ZrusScientific Research Institute, Ochapovsky Regional Clinical Hospital no. 1Инновационная медицина Кубани2541-98972019-09-0103253110.35401/2500-0268-2019-15-3-25-31196Application of chitosan-based wound coatings ‘ChitoPran’ in the treatment of patients with burn traumaA. V. Polyakov0S. B. Bogdanov1I. M. Afanasov2A. V. Karakulev3Y. A. Bogdanova4E. V. Zinoviev5K. F. Osmanov6Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1; Kuban State Medical UniversityScientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1; Kuban State Medical UniversityMoscow State University named after M.V. LomonosovScientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1Kuban State Medical UniversitySaint Petersburg Scientific Research Institute named after I.I. Djanelidze; Saint Petersburg State Pediatric Medical UniversitySaint Petersburg State Pediatric Medical UniversityIntroduction. The analysis of clinical experience for using biodegradable wound coating based on «HitoPran» chitosan in treatment of patients with burn trauma is presented.Background. Our work included an analysis of clinical experience for using a biodegradable wound coating based on «HitoPran» chitosan for surgical treatment in patients with local and common thermal burns.Material and Methods. A treatment analysis was conducted in 46 male and female patients, aged from 1 to 63 years with thermal burns on an area of 5 to 56% of the body surface. All injured were given surgical treatment in the complex with the use of low-temperature air plasma of arc discharge with atmospheric pressure in the conditions of our burn center in 2017–2018. Depending on the area and depth of the lesion, the patients were divided into two clinical groups: with local burns of II degree and area to 5% of the body surface and common burns of II and III degree and body surface 10% and more. In the course of early surgical treatment in patients with local border burns, the use of the wound coating «HitoPran» allows to achieve spontaneous epithelialization of wounds in dry environment after dermabrasion or escharotomy within the surface layers of dermis due to chitosan adhesion to the wound bottom, to reduce the number of dressings in the postoperative period. Covering skin grafts with perforation index 1:4 and 1:6 with wound «ChitoPran» coating in case of autodermoplasty in deep burn wounds provides satisfactory cellular epithelialization, reduces risk of regression of grafts, reduces consumption of wound coating and dressing material.Conclusion. Application of Russian modern biodegradable coatings based on «HitoPran» chitosan in complex treatment in patients with local and common burns with different depth allows to optimize local treatment of burn injuries, as well as to reduce the cost of used dressing material in comparison with foreign alternatives.https://www.innovmedkub.ru/jour/article/view/207woundburn injurywound coveringsurgical treatmentchitosan |
| spellingShingle | A. V. Polyakov S. B. Bogdanov I. M. Afanasov A. V. Karakulev Y. A. Bogdanova E. V. Zinoviev K. F. Osmanov Application of chitosan-based wound coatings ‘ChitoPran’ in the treatment of patients with burn trauma Инновационная медицина Кубани wound burn injury wound covering surgical treatment chitosan |
| title | Application of chitosan-based wound coatings ‘ChitoPran’ in the treatment of patients with burn trauma |
| title_full | Application of chitosan-based wound coatings ‘ChitoPran’ in the treatment of patients with burn trauma |
| title_fullStr | Application of chitosan-based wound coatings ‘ChitoPran’ in the treatment of patients with burn trauma |
| title_full_unstemmed | Application of chitosan-based wound coatings ‘ChitoPran’ in the treatment of patients with burn trauma |
| title_short | Application of chitosan-based wound coatings ‘ChitoPran’ in the treatment of patients with burn trauma |
| title_sort | application of chitosan based wound coatings chitopran in the treatment of patients with burn trauma |
| topic | wound burn injury wound covering surgical treatment chitosan |
| url | https://www.innovmedkub.ru/jour/article/view/207 |
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