Single-cell RNA sequencing reveals the immune features and viral tropism in the central nervous system of mice infected with Japanese encephalitis virus

Single-cell RNA sequencing reveals the immune features and viral tropism in the central nervous system of mice infected with Japanese encephalitis virus

Abstract Japanese encephalitis virus (JEV) is a neurotropic pathogen that causes lethal encephalitis. The high susceptibility and massive proliferation of JEV in neurons lead to extensive neuronal damage and inflammation within the central nervous system. Despite extensive research on JEV pathogenes...

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Bibliographic Details
Main Authors: Ling’en Yang, Junyao Xiong, Yixin Liu, Yinguang Liu, Xugang Wang, Youhui Si, Bibo Zhu, Huanchun Chen, Shengbo Cao, Jing Ye
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Neuroinflammation
Subjects:
JEV
scRNA-seq
Neuron
Baiap2
Inflammation
Online Access:https://doi.org/10.1186/s12974-024-03071-1

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