Boronic acid-functionalized tungsten disulfide quantum dots as a fluorescence probe for sensitive detection of dopamine
A fluorescence probe comprising boronic acid-functionalized tungsten disulfide quantum dots for the label-free detection of dopamine was developed. The detection method is based on the selective interaction between diols and aminophenylboronic acid. This interaction generates quenching of fluorescen...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Biosensors and Bioelectronics: X |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590137022000632 |
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| author | Rashmita Devi Satyabrat Gogoi Hemant Sankar Dutta Prakash Jyoti Saikia Ayushi Singhal Raju Khan |
| author_facet | Rashmita Devi Satyabrat Gogoi Hemant Sankar Dutta Prakash Jyoti Saikia Ayushi Singhal Raju Khan |
| author_sort | Rashmita Devi |
| collection | DOAJ |
| description | A fluorescence probe comprising boronic acid-functionalized tungsten disulfide quantum dots for the label-free detection of dopamine was developed. The detection method is based on the selective interaction between diols and aminophenylboronic acid. This interaction generates quenching of fluorescence due to aggregation and the inner filter effect of the fabricated fluorescence probe. The proposed method allows the determination of dopamine in the concentration range from 0.05 μM to 100 μM including a correlation coefficient of 0.9925 along with a low detection limit of 0.01 μM. It manifests a better selectivity towards dopamine in the existence of different interfering analytes. Furthermore, the applicability of the proposed method has been utilized in the real sample which showed promising results for diagnostic purposes. |
| first_indexed | 2024-04-11T14:24:48Z |
| format | Article |
| id | doaj.art-b4183bfdcc0d4fa9822e3a8aaf6885f4 |
| institution | Directory Open Access Journal |
| issn | 2590-1370 |
| language | English |
| last_indexed | 2024-04-11T14:24:48Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Biosensors and Bioelectronics: X |
| spelling | doaj.art-b4183bfdcc0d4fa9822e3a8aaf6885f42022-12-22T04:18:55ZengElsevierBiosensors and Bioelectronics: X2590-13702022-09-0111100168Boronic acid-functionalized tungsten disulfide quantum dots as a fluorescence probe for sensitive detection of dopamineRashmita Devi0Satyabrat Gogoi1Hemant Sankar Dutta2Prakash Jyoti Saikia3Ayushi Singhal4Raju Khan5Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, U.P., 201002, India; Analytical Chemistry Group, Material Sciences and Technology Division, CSIR-North East Institute of Science & Technology (CSIR-NEIST), Jorhat, 785006, IndiaDepartment of Chemistry, School of Basic Sciences, Assam Kaziranga University, Jorhat, Assam, IndiaAcademy of Scientific and Innovative Research (AcSIR), Ghaziabad, U.P., 201002, India; Analytical Chemistry Group, Material Sciences and Technology Division, CSIR-North East Institute of Science & Technology (CSIR-NEIST), Jorhat, 785006, IndiaAcademy of Scientific and Innovative Research (AcSIR), Ghaziabad, U.P., 201002, India; Analytical Chemistry Group, Material Sciences and Technology Division, CSIR-North East Institute of Science & Technology (CSIR-NEIST), Jorhat, 785006, IndiaAcademy of Scientific and Innovative Research (AcSIR), Ghaziabad, U.P., 201002, India; Industrial Waste Utilization, Nano and Biomaterials, CSIR-Advanced Materials and Processes Research Institute (AMPRI), Hoshangabad Road, Bhopal - 462026, Madhya Pradesh, IndiaAcademy of Scientific and Innovative Research (AcSIR), Ghaziabad, U.P., 201002, India; Industrial Waste Utilization, Nano and Biomaterials, CSIR-Advanced Materials and Processes Research Institute (AMPRI), Hoshangabad Road, Bhopal - 462026, Madhya Pradesh, India; Corresponding author. CSIR-Advanced Materials and Processes Research Institute (AMPRI), Hoshangabad Road, Bhopal - 462026, Madhya Pradesh, India.A fluorescence probe comprising boronic acid-functionalized tungsten disulfide quantum dots for the label-free detection of dopamine was developed. The detection method is based on the selective interaction between diols and aminophenylboronic acid. This interaction generates quenching of fluorescence due to aggregation and the inner filter effect of the fabricated fluorescence probe. The proposed method allows the determination of dopamine in the concentration range from 0.05 μM to 100 μM including a correlation coefficient of 0.9925 along with a low detection limit of 0.01 μM. It manifests a better selectivity towards dopamine in the existence of different interfering analytes. Furthermore, the applicability of the proposed method has been utilized in the real sample which showed promising results for diagnostic purposes.http://www.sciencedirect.com/science/article/pii/S2590137022000632DopamineBoronic acidFluorescenceTungsten disulfide quantum dots |
| spellingShingle | Rashmita Devi Satyabrat Gogoi Hemant Sankar Dutta Prakash Jyoti Saikia Ayushi Singhal Raju Khan Boronic acid-functionalized tungsten disulfide quantum dots as a fluorescence probe for sensitive detection of dopamine Biosensors and Bioelectronics: X Dopamine Boronic acid Fluorescence Tungsten disulfide quantum dots |
| title | Boronic acid-functionalized tungsten disulfide quantum dots as a fluorescence probe for sensitive detection of dopamine |
| title_full | Boronic acid-functionalized tungsten disulfide quantum dots as a fluorescence probe for sensitive detection of dopamine |
| title_fullStr | Boronic acid-functionalized tungsten disulfide quantum dots as a fluorescence probe for sensitive detection of dopamine |
| title_full_unstemmed | Boronic acid-functionalized tungsten disulfide quantum dots as a fluorescence probe for sensitive detection of dopamine |
| title_short | Boronic acid-functionalized tungsten disulfide quantum dots as a fluorescence probe for sensitive detection of dopamine |
| title_sort | boronic acid functionalized tungsten disulfide quantum dots as a fluorescence probe for sensitive detection of dopamine |
| topic | Dopamine Boronic acid Fluorescence Tungsten disulfide quantum dots |
| url | http://www.sciencedirect.com/science/article/pii/S2590137022000632 |
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